A new technology to improve DNA and RNA testing methods
Official title: A probe-based higher order multiplex technology to expand the capacity of digital PCR systems
Funded at Kasa Bio, L.l.c. · NIH-11183168 · Data updated 2026-11-12
This study is working on a new testing method that can quickly check for several DNA or RNA markers at once, making it easier and cheaper for labs to provide accurate diagnoses for conditions like acute lymphoblastic leukemia, which could help patients get the care they need faster.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kasa Bio, L.l.c. NIH-funded |
| Lab location | 1 site (Peachtree Corners, UNITED STATES) |
| Project start | May 1, 2025 |
| Project end | April 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $345,285 |
| NIH project number | 1R43GM160998-01 |
| Project ID | NIH-11183168 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with acute lymphoblastic leukemia or other conditions requiring precise biomarker quantification.
✕Less likely to help
Patients with conditions that do not involve DNA or RNA biomarker testing may not receive any benefit from this research.
What this research studies
This research focuses on developing a novel multiplexing technology for digital PCR systems, which allows for the simultaneous detection of multiple DNA or RNA biomarkers. By enhancing the capacity and reducing costs associated with current digital PCR methods, this approach aims to make testing more accessible and efficient for clinical laboratories. The technology seeks to minimize the amount of clinical samples needed and reduce environmental waste, making it a more sustainable option for biomarker quantification. Patients may benefit from more accurate and timely diagnoses of conditions like acute lymphoblastic leukemia through improved testing methods.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and cost-effective testing for various cancers, improving patient outcomes.
How similar studies have gone: Other research has shown promise in enhancing digital PCR technologies, indicating that this approach could lead to significant advancements in biomarker testing.
Where this research is happening
-
Kasa Bio, L.l.c.
Peachtree Corners, United States Active
Researchers
- Principal investigator: Madanahally Divakar, Kiran — Kasa Bio, L.l.c.
- Study coordinator: Madanahally Divakar, Kiran
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.