A new test to analyze gene expression in lymphoma patients
A multiplex platform for quantitative analysis of clinically important gene expression signatures
['FUNDING_SBIR_1'] · KASA BIO, L.L.C. · NIH-10920595
This study is testing a new test that helps doctors understand the different types of diffuse large B-cell lymphoma (DLBCL) so they can choose the best treatment for patients, making the process quicker and more affordable.
Quick facts
| Phase | ['FUNDING_SBIR_1'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | KASA BIO, L.L.C. (nih funded) |
| Locations | 1 site (Peachtree Corners, UNITED STATES) |
| Trial ID | NIH-10920595 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel assay to analyze gene expression signatures in patients with diffuse large B-cell lymphoma (DLBCL), the most common and aggressive form of lymphoma. The proposed Zip-MeltTM DLBCL Classifier Assay will allow for the differentiation of two major subtypes of DLBCL, which is crucial for determining the most effective treatment. By utilizing a single reaction to analyze multiple genes, this approach aims to reduce healthcare costs and improve turnaround times for results, making it more accessible for clinical use. Patients will benefit from a more efficient diagnostic process that can lead to better-targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with diffuse large B-cell lymphoma, particularly those needing subtype differentiation for treatment planning.
Not a fit: Patients with other types of lymphoma or those not diagnosed with diffuse large B-cell lymphoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and cost-effective diagnostics for lymphoma patients, improving treatment outcomes.
How similar studies have performed: Similar multiplexing approaches in gene expression analysis have shown promise in other cancers, indicating potential success for this novel assay.
Where this research is happening
Peachtree Corners, UNITED STATES
- KASA BIO, L.L.C. — Peachtree Corners, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MADANAHALLY DIVAKAR, KIRAN — KASA BIO, L.L.C.
- Study coordinator: MADANAHALLY DIVAKAR, KIRAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers, neoplasm/cancer