A new method to record brain activity across the entire brain simultaneously.

Volumetric Mesoscopic Electrophysiology: A New Recording Modality with a Unique Functional Profile and Wide Range of Applications

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-11026557

This study is testing a new way to record brain activity in monkeys to help us better understand how the brain works and how it can be affected by diseases, which could eventually help people with neurological conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-11026557 on NIH RePORTER

What this research studies

This research aims to develop a novel technique called mesoscopic electrophysiology that allows for simultaneous recording of brain activity across the entire brain in non-human primates. By combining the strengths of existing imaging methods like fMRI and electrophysiology, this approach seeks to provide both high spatial and temporal resolution. This could lead to better understanding of brain functions and diseases, ultimately bridging the gap between animal studies and human applications. The research will involve advanced technology to capture brain signals in real-time, which could enhance our knowledge of neurological conditions.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research are individuals with neurological conditions that affect brain function.

Not a fit: Patients with conditions unrelated to brain function or those who do not have access to the research facilities may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic and therapeutic strategies for brain-related disorders.

How similar studies have performed: While the approach is innovative, similar methodologies have shown promise in enhancing our understanding of brain activity, suggesting potential for success.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.