A new catheter to help endograft placement for acute aortic dissection
Official title: Aortic dissection flap division by novel electrosurgical catheter facilitates aortic endograft landing zones
Funded at Cutcath LLC · NIH-11371187 · Data updated 2026-11-12
A new, minimally invasive device is being tested to help doctors place endografts more safely in patients with acute aortic dissection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cutcath LLC NIH-funded |
| Lab location | 1 site (Bloomfield Hills, UNITED STATES) |
| Project start | July 15, 2025 |
| Project end | December 31, 2026 |
| Funding year | 2026 |
| Award (this year) | $200,604 |
| NIH project number | 5R41HL178190-02 |
| Project ID | NIH-11371187 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with acute aortic dissection who are candidates for TEVAR/EVAR and may benefit from improved landing zones.
✕Less likely to help
Patients unsuitable for TEVAR/EVAR or with conditions that contraindicate endovascular repair may not benefit.
What this research studies
This project uses a novel dissection septum cutting catheter to create better landing zones for TEVAR or EVAR procedures in patients with acute aortic dissection. It is a Phase I STTR study conducted by CutCath LLC to assess safety and practical use of the device during endovascular repair. The aim is to make endovascular treatment feasible for more patients and reduce complication risks compared with traditional open surgery.
Why it matters
Potential benefit: If successful, the device could expand the use of less invasive repair for acute aortic dissection and lower procedure-related complications.
How similar studies have gone: Prior endovascular approaches have shown benefits over open surgery, but this device targets a specific technical challenge to improve success rates.
Where this research is happening
-
Cutcath LLC
Bloomfield Hills, United States Active
Researchers
- Principal investigator: Berguer, Ramon — Cutcath LLC
- Study coordinator: Berguer, Ramon
Related research
Other NIH-funded projects on the same topics.
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Improving Outcomes in Vascular Disease for Aortic Dissection: Upfront TEVAR vs Surveillance
A large US study will compare starting treatment with a repair procedure plus medicine to medicine alone with careful follow-up in people with uncomplicated type B aortic dissection.
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Improving Outcomes in Aortic Dissection: Upfront TEVAR vs Surveillance (IMPROVE-AD) for Uncomplicated Type B Dissection
A large, patient-friendly study will compare starting with medicine plus an upfront TEVAR procedure versus medicine with careful monitoring for people with uncomplicated type B aortic dissection.
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IMPROVE-AD: Better outcomes for uncomplicated type B aortic dissection
A large patient study in the US will compare starting with medical care plus upfront TEVAR versus medical care with monitoring alone to see which approach leads to better outcomes for people with uncomplicated type B aortic dissection.
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Upfront TEVAR plus medical therapy vs lifelong monitoring for uncomplicated type B aortic dissection
A large US study tests whether adding early TEVAR to standard medical care helps people with uncomplicated type B aortic dissection live better than medical care alone with ongoing monitoring.
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Non-invasive 4D flow MRI to predict risk in aortic dissection
A study using 4D flow MRI to help doctors predict which patients with aortic dissection are at higher long-term risk so they can tailor treatment.
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Early aortic stent plus medicine versus medicine with watchful waiting for uncomplicated type B aortic dissection
This compares giving an early aortic stent graft plus medicines to using medicines with close follow-up for people with uncomplicated type B aortic dissection to find which approach leads to better outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.