Targeted pelvic warmth/cooling device to relieve pelvic pain
Official title: Targeted Temperature Modulation with Smart Radiometric Monitoring for Effective and Long-Lasting Opioid-Free Pelvic Pain Relief - A Novel Low-Cost, Portable, Tampon-sized Thermal Transfer Device.
Funded at H3pelvic Therapy Systems, INC. · NIH-11410620 · Data updated 2026-11-12
A low-cost, portable device uses controlled temperature changes to soothe pelvic pain from conditions like endometriosis and bladder issues, with the goal of reducing pain and inflammation without opioids.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H3pelvic Therapy Systems, INC. NIH-funded |
| Lab location | 1 site (Lewisville, United States) |
| Project start | September 25, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,099,999 |
| NIH project number | 2R44HD112219-02A1 |
| Project ID | NIH-11410620 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with chronic pelvic pain conditions such as endometriosis, interstitial cystitis/painful bladder syndrome, or related pelvic pain disorders.
✕Less likely to help
People without pelvic pain conditions or those unable to tolerate or access temperature-based therapy may not benefit.
What this research studies
This project aims to finish turning a compact temperature-modulation system into a market-ready medical device that targets pelvic organs. It builds on prior modelling, tissue studies, and live-animal work to show that cooling or warming the vaginal, rectal, or bladder walls can lessen pain. The approach combines advanced thermal transfer, user-friendly electronics, ergonomic design, and a mobile app to safely deliver targeted therapy. If successful, patients with chronic pelvic pain could experience meaningful relief and improved quality of life without opioid medications.
Why it matters
Potential benefit: If successful, patients with pelvic pain could experience reduced pain and better function with a non-drug treatment.
How similar studies have gone: Previous work demonstrated safe and effective temperature modulation in preclinical models, supporting progression to a market-ready device.
Where this research is happening
-
H3pelvic Therapy Systems, INC.
Lewisville, United States Active
Researchers
- Principal investigator: Lyon, Zachary W — H3pelvic Therapy Systems, INC.
- Study coordinator: Lyon, Zachary W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.