Condition

Urinary Bladder Neoplasms clinical trials and research

• 20Clinical trials
• 1New in 30 days
• 32Countries

Newest Urinary Bladder Neoplasms clinical trials

All recruiting trials (20)

• Inactivated UPEC-FimON for Bladder Cancer After BCG or Intravesical Therapy Failure

  This phase 1 study tests whether intravesical doses of inactivated UPEC-FimON are safe and tolerable in adults with non-muscle invasive bladder cancer that progressed after BCG or intravesical therapy.

  Recruiting at 3 sites Phase 1 Hopec Pharma · Kfar Saba, Central District and 2 other locations · NCT07881666

• Alpha1H before bladder tumor surgery in low/intermediate risk non-muscle-invasive bladder cancer

  This trial tests whether putting Alpha1H directly into the bladder before standard surgery helps prevent cancer from coming back or getting worse in adults with low- to intermediate-risk non-muscle-invasive bladder cancer.

  Recruiting Phase 3 Hamlet Pharma AB · Prague · NCT07804056

• Understanding how high-risk non-muscle-invasive bladder cancer is diagnosed and cared for in Portugal

  This study looks at how patients with high-risk non-muscle-invasive bladder cancer have been diagnosed and treated in regular care in Portugal.

  Recruiting Janssen-Cilag Farmaceutica Ltda. · Lisbon · NCT07784387

• Benchmarking AI language models against tumor boards for oncology treatment decisions

  This project tests whether frontier AI language models can match the treatment recommendations of multidisciplinary tumor boards for common cancers using standardized synthetic cases.

  Recruiting Assistance Publique - Hôpitaux de Paris · Boulogne-Billancourt and 4 other locations · NCT07739121

• Real-world look at high-risk non-muscle-invasive bladder cancer after BCG in Korea

  This study tests how people with high-risk non-muscle-invasive bladder cancer fare after BCG therapy in real-world clinical settings in Korea.

  Recruiting Janssen Korea, Ltd., Korea · Suwon · NCT07735793

• Enfortumab vedotin plus pembrolizumab versus chemoradiotherapy for muscle-invasive bladder cancer

  This trial tests whether combining enfortumab vedotin with pembrolizumab can help people with non-metastatic muscle-invasive bladder cancer keep their bladder and control the cancer better than standard concurrent chemoradiotherapy.

  Recruiting at 29 sites Phase 3 Astellas Pharma Inc · Little Rock, Arkansas and 28 other locations · NCT07566156

• Early versus delayed Blad‑Care (hyaluronic acid + chondroitin) during BCG therapy

  This trial will test whether giving Blad‑Care (hyaluronic acid and chondroitin sulfate) early during BCG treatment reduces bladder irritation in adults with non‑muscle‑invasive bladder cancer.

  Recruiting BLAD-HYA Group · Seoul, Dongdaemun-gu · NCT07495072

• MK-3120 treatment for high-risk non‑muscle invasive bladder cancer (CIS ± papillary)

  We will test whether MK-3120 can be given safely and is tolerated by people with high‑risk non‑muscle invasive bladder cancer after tumor removal (TURBT).

  Recruiting at 12 sites Phase 1/2 Merck Sharp & Dohme LLC · Bakersfield, California and 16 other locations · NCT07222488

• Vepugratinib with enfortumab vedotin and pembrolizumab for FGFR3‑altered advanced urothelial cancer

  This trial tests whether adding vepugratinib to enfortumab vedotin and pembrolizumab helps people with advanced or metastatic urothelial (bladder) cancer who have an FGFR3 genetic change, compared with placebo.

  Recruiting at 129 sites Phase 3 Eli Lilly and Company · Tucson, Arizona and 275 other locations · NCT07218380

• Using durvalumab with chemotherapy for muscle-invasive bladder cancer

  This study is testing if adding a new immune therapy called durvalumab to standard chemotherapy can help people with muscle-invasive bladder cancer before they have surgery.

  Recruiting at 48 sites Phase 2 AstraZeneca · Chermside and 58 other locations · NCT06960577

• Comparing 3 vs 6 cycles of chemotherapy followed by avelumab for advanced bladder cancer

  This study is testing whether giving 3 or 6 cycles of chemotherapy followed by avelumab can improve the quality of life for people with advanced bladder cancer.

  Recruiting at 2 sites Phase 2 Queen Mary University of London · Paris and 2 other locations · NCT06892860

• New treatment for high-risk non-muscle invasive bladder cancer

  This study is testing a new treatment combining Intismeran autogene with BCG to see if it can help people with high-risk non-muscle invasive bladder cancer who haven't responded to standard BCG therapy.

  Recruiting at 84 sites Phase 2 Merck Sharp & Dohme LLC · Bakersfield, California and 88 other locations · NCT06833073

• Effect of BCG and Tislelizumab on Bladder Cancer

  This study is testing if combining a vaccine called BCG with a new drug called tislelizumab can help people with intermediate and high-risk bladder cancer have fewer recurrences after surgery.

  Recruiting Phase 3 Fujian Medical University Union Hospital · Fuzhou, Fujian · NCT06441110

• Using advanced imaging to diagnose and predict treatment outcomes for bladder cancer

  This study is testing new imaging techniques to see if they can better diagnose muscle-invasive bladder cancer and predict how well patients will respond to chemotherapy.

  Recruiting First Affiliated Hospital of Fujian Medical University · Fuzhou, Fujian · NCT06421142

• Evaluating HTL0039732 for Advanced Solid Tumours

  This study is testing a new drug called HTL0039732, alone and with another treatment, to see if it can help people with advanced solid tumors by boosting their immune response against cancer.

  Recruiting at 6 sites Phase 1/2 Cancer Research UK · Cambridge and 5 other locations · NCT05944237

• Evaluating LOXO-435 for treating cancer with FGFR3 gene changes

  This study is testing a new cancer drug called LOXO-435 to see if it can safely help people with advanced tumors that have changes in the FGFR3 gene, either on its own or with standard treatments.

  Recruiting at 82 sites Phase 1 Eli Lilly and Company · Tucson, Arizona and 82 other locations · NCT05614739

• Understanding lymphedema after urologic surgery

  This study looks at how often and how badly lymphedema affects people after they have surgery for urologic cancer that involves removing lymph nodes.

  Recruiting at 2 sites Vastra Gotaland Region · Gothenburg and 1 other locations · NCT05264337

• Testing a new drug for advanced solid tumors

  This study is testing a new drug called sigvotatug vedotin to see if it can safely help people with advanced solid tumors, both on its own and with other treatments.

  Recruiting at 145 sites Phase 1 Seagen Inc. · Anchorage, Alaska and 157 other locations · NCT04389632

• Using MRI with contrast to assess bladder cancer staging

  This study is testing a new type of MRI with a special contrast solution to see if it can help doctors better understand the stage of bladder cancer in patients before surgery.

  Recruiting Early Phase 1 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT04369560

• Collecting data for bladder cancer patients

  This study is collecting information from bladder cancer patients to help improve future treatments and understand how the disease behaves.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT03973671

Related topics

Quick answers

How many Urinary Bladder Neoplasms clinical trials are recruiting right now?

20, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 32 countries. The most sites are in France (8 trials), Spain (7 trials), United States (7 trials), South Korea (6 trials), Canada (6 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 4, Phase 2: 3, Phase 1: 3, Phase 1/2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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