Condition

Stage II Bladder Cancer AJCC v8 clinical trials and research

• 5Clinical trials
• 2Countries

Newest Stage II Bladder Cancer AJCC v8 clinical trials

All recruiting trials (5)

• ctDNA-based monitoring in muscle-invasive bladder cancer

  This study tests whether a blood-based ctDNA test can flag residual or returning disease in adults with muscle-invasive bladder cancer undergoing standard treatments.

  Recruiting OHSU Knight Cancer Institute · Portland, Oregon · NCT07726602

• Shorter-course versus standard-course radiation with chemotherapy for muscle-invasive bladder cancer

  This trial tests whether a much shorter course of radiation plus standard chemotherapy works as well as the usual shorter radiation schedule for people with muscle-invasive bladder cancer who are pursuing bladder-preserving treatment.

  Recruiting at 247 sites Phase 3 NRG Oncology · Fairbanks, Alaska and 258 other locations · NCT07097142

• Immunotherapy plus radiation to avoid bladder removal after chemo for muscle-invasive bladder cancer

  This phase II test gives pembrolizumab with radiation after chemotherapy to try to help people with muscle-invasive bladder cancer keep their bladders instead of having them removed.

  Recruiting at 171 sites Phase 2 National Cancer Institute (NCI) · Birmingham, Alabama and 181 other locations · NCT07061964

• Combining enfortumab vedotin and pembrolizumab with radiation for muscle invasive bladder cancer

  This study is testing a new combination of a drug and radiation therapy to see if it helps people with muscle invasive bladder cancer who want to avoid surgery.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT06470282

• Combining futibatinib and durvalumab before bladder cancer surgery for patients who can't use cisplatin

  This study is testing if combining two drugs, futibatinib and durvalumab, before bladder cancer surgery can help patients who can't take cisplatin feel better and improve their chances of recovery.

  Recruiting at 2 sites Phase 2 Ohio State University Comprehensive Cancer Center · Ann Arbor, Michigan and 2 other locations · NCT06263153

Related topics

Quick answers

How many Stage II Bladder Cancer AJCC v8 clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (5 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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