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SCLC, Extensive Stage clinical trials and research

• 10Clinical trials
• 1Country

Newest SCLC, Extensive Stage clinical trials

All recruiting trials (10)

• YL201 plus serplulimab vs the usual chemo combo as first treatment for extensive-stage small cell lung cancer

  This trial tests whether adding YL201 to serplulimab can improve outcomes compared with standard carboplatin and etoposide plus serplulimab in adults with treatment-naïve extensive-stage SCLC.

  Recruiting at 2 sites Phase 3 MediLink Therapeutics (Suzhou) Co., Ltd. · Guangzhou, Guangdong and 1 other locations · NCT07739758

• Using a new PFD3 PET tracer to find and stage small cell lung cancer

  This test will try a new PET tracer called PFD3 in adults with small cell lung cancer to see if it detects tumors and stages disease more accurately than standard FDG PET/CT.

  Recruiting Phase 1/2 Peking University First Hospital · Beijing, Beijing Municipality · NCT07508852

• Adaptive Phase 1/2 testing dual-target CAR‑NK cells for relapsed or refractory small cell lung cancer

  This trial tests off-the-shelf dual-target CAR‑NK cell therapy in adults with relapsed or refractory extensive-stage small cell lung cancer to see if it is safe and can shrink tumors.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07480213

• Maintenance treatment with [225Ac]Ac-DOTATATE plus tislelizumab for extensive‑stage small cell lung cancer with somatostatin receptor–positive tumors

  This trial will try to see if adding a targeted radioligand ([225Ac]Ac‑DOTATATE) to the immunotherapy drug tislelizumab as maintenance helps people with extensive‑stage small cell lung cancer whose tumors are somatostatin receptor positive after first‑line treatment.

  Recruiting Phase 1 Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT07413042

• Safety and tolerability of NEUK203-13 CAR-NK cells for DLL3 in advanced neuroendocrine tumors

  This early phase trial tests NEUK203-13, an off-the-shelf CAR-NK cell therapy, in adults with advanced SCLC or other neuroendocrine tumors to see if it is safe and if it shows any anti-tumor activity.

  Recruiting Phase 1 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing · NCT07366658

• Bemotuzumab with chemotherapy and anlotinib, then targeted radiotherapy for extensive-stage small cell lung cancer

  This phase 2 study tests whether a combination of bemotuzumab, chemotherapy, and anlotinib, followed by continued bemotuzumab and anlotinib with thoracic radiotherapy, can help untreated extensive-stage small cell lung cancer.

  Recruiting Phase 2 Tianjin Medical University Cancer Institute and Hospital · Tianjin, Tianjin Municipality · NCT07358676

• ABP1011T tablets for people with advanced solid tumors, including small cell lung cancer

  This trial will test whether taking ABP1011T tablets daily can help people with advanced solid tumors, especially those with small cell lung cancer who have already had other treatments.

  Recruiting at 3 sites Phase 2 Shanghai AB PharmaTech Ltd. · Luoyang, Henan and 7 other locations · NCT07321574

• Olvi-Vec with platinum plus etoposide for late-stage small cell lung cancer

  This test tries adding an oncolytic virus called Olvi-Vec to standard platinum-plus-etoposide chemotherapy for people with late-stage small cell lung cancer.

  Recruiting at 2 sites Phase 1/2 Newsoara HYK Biopharmaceutical (Shanghai) Co., Ltd. · Hangzhou and 1 other locations · NCT07136285

• Golidocitinib plus PD-1 inhibitor maintenance for previously untreated extensive-stage small cell lung cancer

  This trial will see if adding golidocitinib to PD-1 inhibitor maintenance helps people with previously untreated extensive-stage small cell lung cancer.

  Recruiting at 2 sites Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing and 1 other locations · NCT07110103

• Adebelizumab with chemotherapy given with radiotherapy at the same time versus after radiotherapy for extensive-stage small cell lung cancer

  This study tests whether adding adebelizumab to chemo and radiotherapy works better when given at the same time as radiotherapy compared to after radiotherapy in adults with extensive-stage SCLC.

  Recruiting Phase 2 Peking University Cancer Hospital & Institute · Beijing, Beijing Municipality · NCT06768307

Related topics

Quick answers

How many SCLC, Extensive Stage clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in China. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 3, Phase 1: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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