Condition

Recurrent Prostate Cancer clinical trials and research

• 9Clinical trials
• 5Countries

Newest Recurrent Prostate Cancer clinical trials

All recruiting trials (9)

• IL-15 superagonist with or without a PSA vaccine in biochemically recurrent prostate cancer after SBRT

  This study tests whether the drug N-803, alone or with a PSA-targeted vaccine, can lower PSA in men with biochemically recurrent prostate cancer after prior SBRT.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07686380

• Terbinafine for prostate cancer with rising PSA after local treatment

  This phase II test gives oral terbinafine to men with biochemical recurrence after definitive local therapy and no visible metastases to see if it slows PSA rise and delays starting hormone therapy.

  Recruiting at 11 sites Phase 2 Swiss Cancer Institute · Baden and 10 other locations · NCT07365423

• DNA vaccine plus nivolumab and targeted radiation for recurrent oligometastatic prostate cancer

  This study will try a DNA vaccine called pTVG-HP together with the checkpoint blocker nivolumab and targeted radiation to see if they can eliminate metastatic tumors in men with non-castrate, recurrent oligometastatic prostate cancer.

  Recruiting Phase 1 University of Wisconsin, Madison · Madison, Wisconsin · NCT07090148

• Combining radiation therapy with hormone treatments for advanced prostate cancer

  This study is testing if combining a specific type of radiation therapy with hormone treatments can help men with advanced prostate cancer live longer and feel better compared to just using radiation alone.

  Recruiting at 3 sites Phase 2 Mayo Clinic · Phoenix, Arizona and 2 other locations · NCT06378866

• Testing enzalutamide and PDS01ADC for recurrent prostate cancer

  This study is testing if a new combination of two treatments, enzalutamide and PDS01ADC, can help people with recurrent prostate cancer feel better and have better results than current options.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT06096870

• Analyzing the tumor environment in metastatic prostate cancer

  This study is trying to learn more about the environment around prostate cancer tumors in men with advanced disease by looking at tissue samples to help find new treatment options.

  Recruiting Columbia University · New York, New York · NCT05304858

• Using PSMA-PET imaging to find early metastatic prostate cancer in men with high Decipher test scores

  This study is testing a new type of imaging to see if it can help find early signs of recurring prostate cancer in men with high-risk test scores.

  Recruiting Phase 2/3 H. Lee Moffitt Cancer Center and Research Institute · Tampa, Florida · NCT03495427

• High dose rate brachytherapy for recurrent prostate cancer

  This study is testing if a special type of radiation therapy can help men with recurrent prostate cancer feel better and control their cancer after previous treatment.

  Recruiting British Columbia Cancer Agency · Kelowna, British Columbia · NCT03246802

• Assessing the safety and effectiveness of the SpectraCure P18 System for recurrent prostate cancer

  This study is testing a new laser treatment for men with recurrent prostate cancer to see if it is safe and effective for those who can't have surgery or other types of radiation.

  Recruiting at 4 sites Phase 1/2 SpectraCure AB · New York, New York and 3 other locations · NCT03067051

Related topics

Quick answers

How many Recurrent Prostate Cancer clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (7 trials), Canada (2 trials), Switzerland (1 trial), Sweden (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1: 1, Phase 2/3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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