Condition

Pouchitis clinical trials and research

• 5Clinical trials
• 9Countries

Newest Pouchitis clinical trials

All recruiting trials (5)

• Etrasimod to Help Prevent Pouchitis After Pouch Surgery

  This study tests whether etrasimod, taken daily, can help prevent pouchitis in adults who had total proctocolectomy with ileal-pouch anal anastomosis for ulcerative colitis and are currently in remission.

  Recruiting Phase 2 Icahn School of Medicine at Mount Sinai · New York, New York · NCT07486921

• Guselkumab and diet for chronic or relapsing pouchitis

  This project will test whether the drug guselkumab plus a high-fruit, low ultra-processed-food diet helps adults with chronic or relapsing pouchitis.

  Recruiting Phase 4 Universitaire Ziekenhuizen KU Leuven · Leuven, Vlaams-Brabant · NCT06916390

• Evaluating the safety and effectiveness of vedolizumab in children and teenagers with chronic pouchitis

  This study is testing if a medication called vedolizumab can help children and teenagers with chronic pouchitis feel better and stay healthy after bowel surgery.

  Recruiting at 14 sites Phase 3 Takeda · Leuven, Vlaams-Brabant and 13 other locations · NCT06443502

• Using rifaximin to prevent recurrent pouchitis after surgery

  This study is testing if taking rifaximin daily for a year can help prevent pouchitis from coming back in people who have had surgery for ulcerative colitis.

  Recruiting at 2 sites Phase 4 University of North Carolina, Chapel Hill · New York, New York and 1 other locations · NCT06312683

• Fecal microbiota transplant for chronic pouchitis treatment

  This study is testing whether a fecal microbiota transplant from healthy donors can help people with chronic pouchitis feel better when other treatments haven't worked.

  Recruiting Early Phase 1 Icahn School of Medicine at Mount Sinai · New York, New York · NCT05829109

Related topics

Quick answers

How many Pouchitis clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (3 trials), Belgium (2 trials), Croatia (1 trial), Czechia (1 trial), Greece (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2, Phase 3: 1, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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