Condition
Post Stroke Depression clinical trials and research
As of November 12, 2026, Find a Trial lists 6 Post Stroke Depression clinical trials that are recruiting, at sites in 4 countries (most in United States (3), Denmark (1), Israel (1)). By phase: Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 6Clinical trials
- 4Countries
Newest Post Stroke Depression clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Hyperbaric oxygen therapy for persistent post-stroke depression | — | Zrifin | Recruiting | Feb 20, 2026 |
| Predicting depression risk after an ischemic stroke | — | Chongqing | Recruiting | Dec 19, 2025 |
| Building physical capacity after chronic stroke | — | Charleston, South Carolina | Recruiting | Jun 26, 2025 |
| Effects of natural light on stroke recovery complications | — | Glostrup Municipality, Capital Region | Recruiting | Apr 10, 2025 |
| Telephone/video behavioral activation to prevent depression after a first stroke in low-income older adults | — | Houston, Texas | Recruiting | Mar 7, 2025 |
| Zuranolone (allopregnanolone) for post-stroke depression | Phase 2 | Durham, North Carolina | Recruiting | Jan 6, 2025 |
All recruiting trials (6)
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Hyperbaric oxygen therapy for persistent post-stroke depression
This research will test whether hyperbaric oxygen therapy can reduce depressive symptoms in adults with long-standing post-stroke depression who are already on antidepressants.
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Predicting depression risk after an ischemic stroke
This project will try to use machine learning on clinical and other patient data to predict which people hospitalized with an acute ischemic stroke will develop depression.
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Building physical capacity after chronic stroke
This 12-week modified cardiac rehabilitation program will try to improve physical fitness and mood in people living with chronic stroke, including those with post-stroke depression.
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Effects of natural light on stroke recovery complications
This study tests if using natural light during rehab can help stroke patients feel less depressed and tired as they recover.
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Telephone/video behavioral activation to prevent depression after a first stroke in low-income older adults
This project will test whether coaching-style behavioral activation delivered by trained lay counselors over phone or video can prevent depression in low-income older adults who recently had a first stroke and currently have mild or no depressive symptoms.
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Zuranolone (allopregnanolone) for post-stroke depression
This trial will test whether a 14-day course of oral zuranolone is safe, well tolerated, and can reduce moderate to severe depression in adults 21–65 who developed depression within a year after a stroke.
Related topics
Quick answers
How many Post Stroke Depression clinical trials are recruiting right now?
6, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in United States (3 trials), Denmark (1 trial), Israel (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.