Effects of natural light on stroke recovery complications

The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation

Not applicable Interventional Rigshospitalet, Denmark · NCT06922409

This study tests if using natural light during rehab can help stroke patients feel less depressed and tired as they recover.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment45 (estimated)
Ages18 Years and up
SexAll
SponsorRigshospitalet, Denmark Academic / other
Locations1 site (Glostrup Municipality, Capital Region)
Trial IDNCT06922409 on ClinicalTrials.gov

What this trial studies

This study investigates how exposure to naturalistic light can influence post-stroke complications such as depression and fatigue in patients undergoing rehabilitation. By utilizing artificial light that mimics the spectrum and rhythm of sunlight, the researchers aim to assess its impact on mental states and circadian regulation. The effects will be measured through questionnaires, MRI scans, and biological markers related to inflammation and sleep. The study focuses on stroke patients who require at least 10 days of rehabilitation.

Who should consider this trial

Good fit: Ideal candidates are stroke patients experiencing moderate to severe fatigue and/or depression who are admitted for rehabilitation.

Not a fit: Patients with severe cognitive impairments, such as those unable to communicate or cooperate, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the mental health and recovery outcomes for stroke patients.

How similar studies have performed: Previous studies have indicated positive outcomes with light therapy in similar contexts, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients scoring moderate-severe fatigue and/or depression OR NO fatigue and/or depressione which are evaluated as candidates for the rehabilitation unit.

Exclusion Criteria:

* GCS \< 15
* No functioning nervus opticus or retina in both eyes
* Unable to open both eyes
* Non communicating patients e.g. severe aphasia (incompetent patients)
* Unable to cooperate to the physical examinations
* Less than 10 days of hospitalization in the rehabilitation department
* Claustrophobia
* If the sub investigator finds the study participant unfit to conduct the investigations

Where this trial is running

Glostrup Municipality, Capital Region

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post Stroke DepressionPost Stroke FatigueCircadian DysregulationStrokecircadian rhythm disruptionLight therapyCircadian Light
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.