Condition
Plexiform Neurofibroma clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Plexiform Neurofibroma clinical trials that are recruiting, at sites in 2 countries (most in United States (2), China (1)). By phase: Phase 2 (1), Phase 1 (1), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Plexiform Neurofibroma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| TQ-B3234 capsules for adults with symptomatic, inoperable NF1 plexiform neurofibromas | Phase 3 | Hefei, Anhui and 28 other locations | Recruiting | Feb 12, 2026 |
| Combination therapy to shrink plexiform neurofibromas in NF1 patients | Phase 1 | Birmingham, Alabama and 7 other locations | Recruiting | Jul 16, 2024 |
| Early selumetinib to try to prevent plexiform neurofibromas in young children with NF1 | Phase 2 | Birmingham, Alabama and 14 other locations | Recruiting | Jan 3, 2024 |
All recruiting trials (3)
-
TQ-B3234 capsules for adults with symptomatic, inoperable NF1 plexiform neurofibromas
This study will see if oral TQ-B3234 capsules can shrink or reduce symptoms from inoperable plexiform neurofibromas in adults with neurofibromatosis type 1 by Week 24 compared with placebo.
-
Combination therapy to shrink plexiform neurofibromas in NF1 patients
This trial tests whether the drugs cabozantinib and selumetinib can be safely given together to see if they help shrink progressive or painful plexiform neurofibromas in adolescents and adults with NF1.
-
Early selumetinib to try to prevent plexiform neurofibromas in young children with NF1
This trial will see if giving selumetinib to young children with NF1 who are at high risk can prevent or slow the development of plexiform neurofibromas.
Related topics
Quick answers
How many Plexiform Neurofibroma clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (2 trials), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1, Phase 1: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.