Condition
Paroxysmal Atrial Fibrillation (PAF) clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Paroxysmal Atrial Fibrillation (PAF) clinical trials that are recruiting, at sites in 17 countries (most in Belgium (2), United States (2), Czechia (2)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 17Countries
Newest Paroxysmal Atrial Fibrillation (PAF) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Intracardiac Echocardiography-guided vs mapping-guided pulsed-field ablation for paroxysmal atrial fibrillation | — | Zagreb and 7 other locations | Recruiting | Aug 19, 2026 |
| FARAFLEX Mapping and Pulsed Field Ablation for Atrial Fibrillation | — | Jonesboro, Arkansas and 12 other locations | Recruiting | May 8, 2026 |
| Grid X mapping for paroxysmal atrial fibrillation | — | Jinan, Shandong and 4 other locations | Recruiting | Feb 19, 2026 |
| Redo AF ablation using the Sphere-9 catheter and Affera system for recurrent paroxysmal and persistent atrial fibrillation | — | Birmingham, Alabama and 29 other locations | Recruiting | Dec 23, 2025 |
| Pulmonary vein isolation plus box isolation of fibrotic areas using the Globe pulsed field system for symptomatic paroxysmal or persistent atrial fibrillation | — | Kaiserslautern | Recruiting | May 15, 2025 |
All recruiting trials (5)
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Intracardiac Echocardiography-guided vs mapping-guided pulsed-field ablation for paroxysmal atrial fibrillation
This trial will test whether using intracardiac echocardiography (ICE) guidance is as safe and effective as three-dimensional mapping guidance for pulsed-field ablation in people with paroxysmal atrial fibrillation undergoing ablation.
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FARAFLEX Mapping and Pulsed Field Ablation for Atrial Fibrillation
This trial tests the FARAFLEX Mapping and PFA System to see if it can safely help adults with drug-refractory paroxysmal or persistent atrial fibrillation.
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Grid X mapping for paroxysmal atrial fibrillation
This study will try the Grid X catheter together with the EnSite X mapping system during catheter ablation to see if it helps Chinese adults with paroxysmal atrial fibrillation.
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Redo AF ablation using the Sphere-9 catheter and Affera system for recurrent paroxysmal and persistent atrial fibrillation
The study will try the Sphere-9 catheter with the Affera ablation and mapping systems for adults who have symptomatic recurrent paroxysmal or persistent atrial fibrillation after one prior ablation.
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Pulmonary vein isolation plus box isolation of fibrotic areas using the Globe pulsed field system for symptomatic paroxysmal or persistent atrial fibrillation
This trial will test whether using the Globe pulsed field system to perform pulmonary vein isolation plus box isolation of fibrotic areas helps people with symptomatic paroxysmal or persistent atrial fibrillation stay free of arrhythmia over 12 months.
Related topics
Quick answers
How many Paroxysmal Atrial Fibrillation (PAF) clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 17 countries. The most sites are in Belgium (2 trials), United States (2 trials), Czechia (2 trials), Ireland (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.