Condition
Paroxysmal AF clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Paroxysmal AF clinical trials that are recruiting, at sites in 13 countries (most in Belgium (4), Czechia (3), Poland (2)). By phase: Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 13Countries
Newest Paroxysmal AF clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Budiodarone for paroxysmal AF: a dose-escalation safety and feasibility study | Phase 2 | Gdynia and 3 other locations | Recruiting | Aug 28, 2026 |
| Left Atrial Appendage Occlusion and Rhythm Restoration in AF Patients | — | Brussels, B CAP R and 15 other locations | Recruiting | Apr 13, 2026 |
| Coherent Sine-Burst Electroporation (CSE) Ablation for Atrial Fibrillation | — | Birmingham, Alabama and 26 other locations | Recruiting | Jan 20, 2025 |
| Pulsed field versus radiofrequency approaches to change vagal nerve effects during pulmonary vein isolation for paroxysmal AF | — | Aalst, Belgium | Recruiting | Oct 17, 2024 |
| Evaluating a new catheter for treating persistent atrial fibrillation | — | Brussels and 3 other locations | Recruiting | Jul 19, 2024 |
All recruiting trials (5)
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Budiodarone for paroxysmal AF: a dose-escalation safety and feasibility study
This study tests whether budiodarone is safe and helps control paroxysmal atrial fibrillation in about 100 adults over 6 months, using dose adjustments guided by AF monitoring.
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Left Atrial Appendage Occlusion and Rhythm Restoration in AF Patients
This trial tests a combined procedure using the Volt PFA System and Amulet 2 to see if it safely and feasibly treats atrial fibrillation while also closing the left atrial appendage in adults with AF.
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Coherent Sine-Burst Electroporation (CSE) Ablation for Atrial Fibrillation
This study will test whether the Argá Medtech CSE electroporation device can safely and effectively ablate heart tissue to treat adults with symptomatic paroxysmal or persistent atrial fibrillation who have not responded to drugs.
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Pulsed field versus radiofrequency approaches to change vagal nerve effects during pulmonary vein isolation for paroxysmal AF
This study tests whether pulsed field ablation, alone or combined with radiofrequency, changes vagal nerve activity during pulmonary vein isolation in people with paroxysmal atrial fibrillation.
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Evaluating a new catheter for treating persistent atrial fibrillation
This study is testing a new catheter to see if it can safely help people with persistent atrial fibrillation who haven't found relief from other treatments.
Related topics
Quick answers
How many Paroxysmal AF clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 13 countries. The most sites are in Belgium (4 trials), Czechia (3 trials), Poland (2 trials), Croatia (2 trials), Lithuania (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.