Condition
Orthostatic Intolerance clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Orthostatic Intolerance clinical trials that are recruiting, at sites in 2 countries (most in Canada (3), United States (2)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 2Countries
Newest Orthostatic Intolerance clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| STAND-UP: opening narrowed veins above the heart to help low blood pressure when standing | — | Roslyn, New York | Recruiting | Sep 29, 2025 |
| How age, sex, and a handgrip affect heart–vessel communication during low blood pressure | — | Boston, Massachusetts | Recruiting | Apr 22, 2025 |
| Improving blood pressure control in children who faint | — | Burnaby, British Columbia | Recruiting | Dec 1, 2022 |
| Assessing counterpressure maneuvers for preventing fainting in children | — | Vancouver, British Columbia | Recruiting | Sep 27, 2022 |
| Effects of CO2 on heart rate and symptoms in POTS patients | — | Calgary, Alberta | Recruiting | Feb 17, 2020 |
All recruiting trials (5)
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STAND-UP: opening narrowed veins above the heart to help low blood pressure when standing
This study will try a minimally invasive catheter procedure to open narrowed supracardiac veins and see if that improves dizziness, fainting, or low blood pressure in adults with orthostatic hypotension or orthostatic intolerance that hasn't improved with standard treatments.
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How age, sex, and a handgrip affect heart–vessel communication during low blood pressure
We will test whether simulated low blood pressure with and without a handgrip exercise changes how the heart and blood vessels communicate in healthy young and older men and women.
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Improving blood pressure control in children who faint
This study is testing if certain movements can help children aged 6-18 who faint feel better by improving their blood pressure and heart function compared to regular advice.
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Assessing counterpressure maneuvers for preventing fainting in children
This study is testing if teaching children techniques to prevent fainting can help them avoid losing consciousness when they visit the emergency room.
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Effects of CO2 on heart rate and symptoms in POTS patients
This study tests if breathing in higher levels of carbon dioxide can help improve heart rate and symptoms for people with Postural Orthostatic Tachycardia Syndrome (POTS).
Related topics
Quick answers
How many Orthostatic Intolerance clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in Canada (3 trials), United States (2 trials). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.