Condition

NSCLC, Stage III clinical trials and research

• 9Clinical trials
• 5Countries

Newest NSCLC, Stage III clinical trials

All recruiting trials (9)

• Adaptive Chemotherapy for PD-L1 High Resectable NSCLC: A Chemo-PHREE Trial

  This study tests cemiplimab in adults with resectable non-small cell lung cancer to see if surgery can be pursued without preceding chemotherapy for some patients.

  Recruiting Phase 2 University of Maryland, Baltimore · Indianapolis, Indiana and 4 other locations · NCT07746388

• Anti-CTLA-4 plus sintilimab and chemotherapy before surgery for resectable Stage II–III NSCLC

  This trial will test whether adding an anti-CTLA-4 antibody (IBI310) to sintilimab plus chemotherapy before surgery helps people with PD-L1–negative, resectable Stage II–III non-small cell lung cancer.

  Recruiting Phase 2 Shanghai Pulmonary Hospital, Shanghai, China · Shanghai, Shanghai Municipality · NCT07410975

• Pilot Precision Exercise Program for Lung Cancer Care

  This pilot will test whether a personalized, virtually supervised home exercise program delivered by telehealth can be implemented and helpful for people with stage II-III non-small cell lung cancer who are receiving chemotherapy or immunotherapy plus surgery.

  Recruiting at 2 sites University of Utah · Galveston, Texas and 1 other locations · NCT06945484

• Testing Repotrectinib in Elderly and Frail Patients with Advanced NSCLC

  This study is testing a new cancer drug called repotrectinib to see if it helps older and frail patients with advanced lung cancer feel better and tolerate the treatment well.

  Recruiting at 20 sites Phase 2 Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer · Aix-en-Provence, Bouches Du Rhône and 19 other locations · NCT06552234

• Combining hormone therapy and immunotherapy for advanced lung cancer

  This study is testing if combining hormone therapy with a type of immunotherapy can help older men with advanced lung cancer respond better to treatment.

  Recruiting Jinzhou Medical University · Zhengzhou, Henan · NCT06512207

• Understanding the diagnosis and treatment of early and locally advanced non-small cell lung cancer

  This study looks at how patients with early and locally advanced non-small cell lung cancer are diagnosed and treated after surgery or radiation to see how well different approaches work.

  Recruiting at 7 sites MSD Italia S.r.l. · San Giovanni Rotondo, FG and 24 other locations · NCT06467383

• Combining anti-PD-1/PD-L1 treatment with UV1 vaccination for advanced lung cancer

  This study is testing if adding a new vaccine to standard lung cancer treatment can help people with advanced non-small cell lung cancer live longer without their disease getting worse.

  Recruiting Phase 2 Vestre Viken Hospital Trust · Drammen, Akershus · NCT05344209

• Predicting durvalumab toxicity using microbiome analysis in lung cancer patients

  This study is testing if the bacteria in the gut can help predict how bad the side effects will be for lung cancer patients taking durvalumab after their treatment.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas and 1 other locations · NCT04680377

• Combining treatments for advanced lung cancer after initial therapy

  This study is testing if adding Tremelimumab and more chemotherapy to the usual treatment can help people with advanced lung cancer do better after their initial therapy.

  Recruiting Phase 3 Stanford University · Stanford, California · NCT04585490

Related topics

Quick answers

How many NSCLC, Stage III clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in United States (4 trials), China (2 trials), Italy (1 trial), France (1 trial), Norway (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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