Condition
Narcolepsy Type 2 clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Narcolepsy Type 2 clinical trials that are recruiting, at sites in 13 countries (most in United States (7), Italy (5), Spain (5)). By phase: Phase 2 (3), Phase 2/3 (3), Phase 3 (1). The most active sponsors are Takeda (2), Centessa Pharmaceuticals plc (2), Alkermes, Inc. (2). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 13Countries
Newest Narcolepsy Type 2 clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Long-term test of TAK-360 in people with narcolepsy or idiopathic hypersomnia | Phase 2/3 | Chula Vista, California and 32 other locations | Recruiting | Jun 15, 2026 |
| Test of Cleminorexton vs placebo for central hypersomnolence in NT1/NT2 | Phase 2/3 | Birmingham, Alabama and 25 other locations | Recruiting | May 20, 2026 |
| ALKS 2680 for adults with Narcolepsy Type 2 | Phase 3 | Cullman, Alabama and 43 other locations | Recruiting | Mar 31, 2026 |
| Long-term ORX750 treatment for people with narcolepsy or idiopathic hypersomnia | Phase 2 | Auburn, Alabama and 23 other locations | Recruiting | Jul 31, 2025 |
| Evaluating TAK-360 for adults with Narcolepsy Type 2 | Phase 2 | Auburn, Alabama and 51 other locations | Recruiting | May 1, 2025 |
| Long-term treatment with ALKS 2680 for narcolepsy and idiopathic hypersomnia | Phase 2/3 | Cullman, Alabama and 49 other locations | Recruiting | Jan 10, 2025 |
| Testing ORX750 for Narcolepsy and Idiopathic Hypersomnia | Phase 2 | Auburn, Alabama and 36 other locations | Recruiting | Dec 31, 2024 |
All recruiting trials (7)
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Long-term test of TAK-360 in people with narcolepsy or idiopathic hypersomnia
This study tests TAK-360 over an extended period to see if it is tolerable for people with narcolepsy type 1, narcolepsy type 2, or idiopathic hypersomnia who completed an earlier TAK-360 trial.
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Test of Cleminorexton vs placebo for central hypersomnolence in NT1/NT2
This study tests cleminorexton to see if it helps daytime sleepiness in adults with Narcolepsy Type 1 or Type 2 compared with a placebo.
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ALKS 2680 for adults with Narcolepsy Type 2
This will test whether ALKS 2680 tablets reduce daytime sleepiness and other symptoms in adults with Narcolepsy Type 2 compared with placebo.
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Long-term ORX750 treatment for people with narcolepsy or idiopathic hypersomnia
This open-label extension will try continued ORX750 treatment in people with narcolepsy or idiopathic hypersomnia who completed the earlier ORX750 parent study.
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Evaluating TAK-360 for adults with Narcolepsy Type 2
This study is testing a new medication called TAK-360 to see if it can help adults with Narcolepsy Type 2 stay awake during the day.
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Long-term treatment with ALKS 2680 for narcolepsy and idiopathic hypersomnia
This study is testing how well a new medication called ALKS 2680 works for people with narcolepsy or idiopathic hypersomnia over a long period of time.
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Testing ORX750 for Narcolepsy and Idiopathic Hypersomnia
This study is testing a new medication called ORX750 to see if it can help people with narcolepsy or idiopathic hypersomnia feel more awake and improve their daily lives.
Related topics
Quick answers
How many Narcolepsy Type 2 clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 13 countries. The most sites are in United States (7 trials), Italy (5 trials), Spain (5 trials), France (4 trials), Canada (3 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 3, Phase 2/3: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.