Condition

Mitral Regurgitation Functional clinical trials and research

• 4Clinical trials
• 3Countries

Newest Mitral Regurgitation Functional clinical trials

All recruiting trials (4)

• Achieving Optimal Medical Therapy Through Transcatheter Mitral Repair in HFrEF

  This trial tests whether early transcatheter edge-to-edge repair (M-TEER) helps patients with HFrEF and secondary MR reach guideline-directed medical therapy faster and more completely, and whether that improves quality of life and outcomes.

  Recruiting University Medical Center Mainz · Mainz, Rhineland-Palatine · NCT07758023

• Mitral Valve Edge-to-Edge Repair for exercise-induced severe mitral regurgitation in heart failure patients

  This trial tests whether adding mitral valve TEER to standard heart failure treatment helps people with exercise-triggered severe mitral regurgitation feel better and stay healthier.

  Recruiting at 2 sites Jena University Hospital · Düsseldorf and 1 other locations · NCT07709208

• Nyra CARLEN System for Functional Mitral Regurgitation

  A first-in-human-feasibility test to see if the CARLEN system is safe and can perform well in people with symptomatic functional mitral valve regurgitation.

  Recruiting at 3 sites Nyra Medical, Inc. · Sacramento, California and 2 other locations · NCT07503236

• Using the Dragonfly system to treat severe mitral regurgitation

  This study is testing a new device called the Dragonfly to see if it can help people with severe mitral regurgitation who still have symptoms despite taking their medications.

  Recruiting Hangzhou Valgen Medtech Co., Ltd · Hangzhou, Zhejiang · NCT04733404

Related topics

Quick answers

How many Mitral Regurgitation Functional clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in Germany (2 trials), United States (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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