Condition

Metastatic Gastric Adenocarcinoma clinical trials and research

• 9Clinical trials
• 19Countries

Newest Metastatic Gastric Adenocarcinoma clinical trials

All recruiting trials (9)

• Subcutaneous versus intravenous tislelizumab with chemotherapy for unresectable or metastatic gastric and gastroesophageal junction adenocarcinoma

  This will test whether giving tislelizumab as a subcutaneous injection instead of an IV infusion, both with chemotherapy, works well and is safe as first treatment for adults with unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma.

  Recruiting at 88 sites Phase 3 BeOne Medicines · Chandler, Arizona and 94 other locations · NCT07043400

• Ivonescimab plus chemotherapy for advanced or metastatic gastric and gastroesophageal adenocarcinoma

  This trial tests whether adding ivonescimab to standard chemotherapy helps adults with advanced or metastatic gastric or gastroesophageal adenocarcinoma respond better to treatment.

  Recruiting at 2 sites Phase 2 Unicancer · Lyon and 3 other locations · NCT06846346

• Nab‑paclitaxel PIPAC with paclitaxel and ramucirumab for stomach cancer that has spread to the peritoneum

  This phase I trial tests whether giving nab‑paclitaxel as a pressurized intraperitoneal aerosol (PIPAC) together with systemic paclitaxel and ramucirumab is safe and can help adults whose stomach cancer has spread to the peritoneal lining after first‑line therapy.

  Recruiting Phase 1 City of Hope Medical Center · Duarte, California · NCT06675136

• Finding the right dose of zongertinib for HER2+ cancer treatment

  This study is testing the best dose of zongertinib to see if it can help adults with hard-to-treat HER2+ cancers shrink their tumors.

  Recruiting at 98 sites Phase 1/2 Boehringer Ingelheim · Cerritos, California and 103 other locations · NCT06324357

• Combining Nivolumab with Standard Treatment for Advanced Stomach or Esophageal Cancer

  This study is testing if adding nivolumab to the usual treatments for advanced stomach or esophageal cancer can help patients live longer and feel better.

  Recruiting at 338 sites Phase 2/3 National Cancer Institute (NCI) · Little Rock, Arkansas and 377 other locations · NCT06203600

• Combining Cyramza, ONIVYDE, and Lonsurf as a second-line treatment for metastatic gastric cancer

  This trial tests whether adding nal-IRI (ONIVYDE) and trifluridine/tipiracil (Lonsurf) to ramucirumab (Cyramza) helps people with metastatic gastric cancer who progressed after one prior systemic therapy.

  Recruiting Phase 1/2 National Health Research Institutes, Taiwan · Taipei, Taiwan/Taipei · NCT05927857

• Comparing two chemotherapy regimens for advanced HER2 negative gastric and esophageal cancer

  This study is testing if a new chemotherapy combination can help people with advanced HER2 negative stomach and esophageal cancer live longer compared to the standard treatment.

  Recruiting at 626 sites Phase 3 Alliance for Clinical Trials in Oncology · Birmingham, Alabama and 801 other locations · NCT05677490

• Personalized vaccine combined with pembrolizumab for advanced solid tumors

  This study is testing a new personalized cancer vaccine combined with pembrolizumab to see if it helps people with advanced solid tumors fight their cancer better.

  Recruiting Phase 1/2 Mayo Clinic · Jacksonville, Florida · NCT05269381

• Combination therapy for gastric cancer with inoperable bowel obstruction

  This study is testing a combination of three cancer drugs to see if it can help people with gastric cancer and a blocked bowel feel better and improve their condition.

  Recruiting Phase 2 Sixth Affiliated Hospital, Sun Yat-sen University · Guangzhou, Guangdong · NCT04840264

Related topics

Quick answers

How many Metastatic Gastric Adenocarcinoma clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 19 countries. The most sites are in United States (6 trials), China (3 trials), France (3 trials), Italy (2 trials), Japan (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 3, Phase 2: 2, Phase 3: 2, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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