Condition
Marginal Zone Lymphoma (MZL) clinical trials and research
As of November 12, 2026, Find a Trial lists 7 Marginal Zone Lymphoma (MZL) clinical trials that are recruiting, at sites in 14 countries (most in United States (3), France (2), Poland (2)). By phase: Phase 1 (4), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 7Clinical trials
- 14Countries
Newest Marginal Zone Lymphoma (MZL) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Orelabrutinib after short-course R-CHOP for people with newly diagnosed marginal zone lymphoma | Phase 2 | Suzhou, Jiangsu | Recruiting | Jan 28, 2026 |
| Safety testing of LTZ-301 in adults with relapsed or refractory B‑cell non-Hodgkin lymphoma | Phase 1 | Duarte, California and 5 other locations | Recruiting | Aug 14, 2025 |
| Testing EXS73565 for patients with relapsed or refractory B-cell cancers | Phase 1 | Tbilisi and 16 other locations | Recruiting | May 20, 2025 |
| Registry platform for patients with blood cancers in Germany | — | Freiburg im Breisgau | Recruiting | Sep 21, 2023 |
| Evaluating NX-5948 for advanced B-cell cancers | Phase 1 | Duarte, California and 61 other locations | Recruiting | Nov 23, 2021 |
| Evaluating NX-2127 for adults with advanced B-cell cancers | Phase 1 | Duarte, California and 15 other locations | Recruiting | Apr 2, 2021 |
| Real-world data collection for lymphoma and patient survival | — | Arras and 36 other locations | Recruiting | Mar 11, 2019 |
All recruiting trials (7)
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Orelabrutinib after short-course R-CHOP for people with newly diagnosed marginal zone lymphoma
This treatment plan will try whether taking orelabrutinib after three cycles of R-CHOP helps people with newly diagnosed marginal zone lymphoma stay in remission.
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Safety testing of LTZ-301 in adults with relapsed or refractory B‑cell non-Hodgkin lymphoma
This trial will test whether LTZ-301 is safe and how it behaves in adults whose B‑cell non-Hodgkin lymphoma has come back or not responded after at least two prior treatments.
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Testing EXS73565 for patients with relapsed or refractory B-cell cancers
This study is testing a new oral medication called EXS73565 to see if it can help adults with B-cell cancers that haven't responded to other treatments.
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Registry platform for patients with blood cancers in Germany
This study is setting up a national registry to collect information from patients with blood cancers in Germany to see how well different treatments work and what patients need.
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Evaluating NX-5948 for advanced B-cell cancers
This study is testing a new drug called NX-5948 to see if it can safely help adults with tough-to-treat B-cell cancers feel better.
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Evaluating NX-2127 for adults with advanced B-cell cancers
This study is testing a new treatment called NX-2127 to see if it can help adults with advanced B-cell cancers feel better and fight their disease.
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Real-world data collection for lymphoma and patient survival
This study is trying to gather real-life information from lymphoma patients to see how different factors affect their treatment success and long-term survival.
Related topics
Quick answers
How many Marginal Zone Lymphoma (MZL) clinical trials are recruiting right now?
7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 14 countries. The most sites are in United States (3 trials), France (2 trials), Poland (2 trials), Spain (2 trials), United Kingdom (2 trials). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 4, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.