Registry platform for patients with blood cancers in Germany

Clinical Research Platform on Treatment, Quality of Life and Outcome of Patients With Hematologic Malignancies (RUBIN) - Extension of Tumor Registry Lymphatic Neoplasms

Observational iOMEDICO AG · NCT06043011

This study is setting up a national registry to collect information from patients with blood cancers in Germany to see how well different treatments work and what patients need.

Quick facts

Study typeObservational
Enrollment2950 (estimated)
Ages18 Years and up
SexAll
SponsoriOMEDICO AG Industry-sponsored
Locations1 site (Freiburg im Breisgau)
Trial IDNCT06043011 on ClinicalTrials.gov

What this trial studies

The RUBIN project aims to establish a national, prospective, longitudinal registry to collect uniform data on patients with hematological malignancies in Germany. This observational study will document patient characteristics, treatment regimens, and disease progression while also gathering patient-reported outcomes. The registry will analyze the effectiveness of various treatments and identify unmet needs in routine care. Additionally, it will create a decentralized biobank for future research.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older with a confirmed diagnosis of specific non-Hodgkin lymphomas.

Not a fit: Patients who have not received systemic therapy for their lymphoid malignancy will not benefit from this study.

Why it matters

Potential benefit: If successful, this registry could improve treatment strategies and patient outcomes for individuals with hematological malignancies.

How similar studies have performed: Other similar registry studies have shown success in improving treatment outcomes and understanding disease progression in hematological malignancies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Confirmed diagnosis of the respective NHL
* If patient is alive: signed written informed consent

  * For patients participating in the PRO survey: IC prior to or at day of start of respective line of treatment.
  * For patients not participating in the PRO survey: IC latest eight weeks after start of respective line of treatment.

Exclusion Criteria:

* No systemic therapy for respective lymphoid malignancy.

Where this trial is running

Freiburg im Breisgau

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Lymphocytic LeukemiaDiffuse Large B-cell LymphomaFollicular LymphomaMantle Cell LymphomaMarginal Zone LymphomaWaldenström's Macroglobulinemianon-Hodgkin lymphoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.