Condition

Locally Advanced Esophageal Squamous Cell Carcinoma clinical trials and research

• 7Clinical trials
• 1Country

Newest Locally Advanced Esophageal Squamous Cell Carcinoma clinical trials

All recruiting trials (7)

• Interferon-gamma plus camrelizumab with chemotherapy before surgery for locally advanced esophageal squamous cell carcinoma

  This trial tests whether giving interferon-gamma with camrelizumab and chemotherapy before surgery helps patients with locally advanced esophageal squamous cell carcinoma.

  Recruiting at 2 sites Phase 2 Hefei Cancer Hospital of the Chinese Academy of Sciences · Hefei, Anhui and 1 other locations · NCT07787273

• Tislelizumab plus chemotherapy to convert unresectable locally advanced esophageal squamous cell carcinoma to surgery

  This study will try whether adding the immune drug tislelizumab to chemotherapy can shrink tumors so people with initially unresectable locally advanced esophageal squamous cell carcinoma can become eligible for surgery.

  Recruiting Shandong Provincial Hospital · Jinan, Shandong · NCT07549100

• Optimizing treatment for advanced esophageal cancer

  This study is testing a new treatment plan that combines chemotherapy, immunotherapy, and radiotherapy to see if it can help people with advanced esophageal cancer feel better and improve their chances of recovery.

  Recruiting Phase 2/3 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT06907602

• Combining Toripalimab with Chemoradiotherapy for Esophageal Cancer

  This study is testing if adding a new drug called Toripalimab to standard chemotherapy and radiation can help people with locally advanced esophageal cancer respond better to treatment before surgery.

  Recruiting Phase 2 Nanfang Hospital, Southern Medical University · Guangzhou, Baiyun District · NCT06843889

• Cadonilimab with paclitaxel micelles and cisplatin before surgery for locally advanced esophageal squamous cancer

  This trial will test whether giving cadonilimab together with paclitaxel polymeric micelles and cisplatin before surgery helps people with locally advanced esophageal squamous cell carcinoma.

  Recruiting Phase 2 The First Affiliated Hospital with Nanjing Medical University · Nanjing, Jiangsu · NCT06356688

• Immunotherapy with radiotherapy and nutrition support for advanced esophageal cancer in patients who can’t tolerate standard chemoradiation

  This trial tests whether adding a PD-1 inhibitor (sintilimab) to radiotherapy plus specialized nutrition helps patients with locally advanced esophageal squamous cell carcinoma who can’t tolerate standard chemoradiation.

  Recruiting at 10 sites Phase 2 Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing, Beijing Municipality and 9 other locations · NCT06342167

• Using Toripalimab after Chemoradiotherapy for Elderly Esophageal Cancer

  This study is testing if the drug toripalimab can help older patients with advanced esophageal cancer feel better and lower their chances of the cancer coming back after they’ve had chemoradiotherapy.

  Recruiting Phase 2 Sun Yat-sen University · Guangzhou, Guangdong · NCT06187597

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Quick answers

How many Locally Advanced Esophageal Squamous Cell Carcinoma clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in China. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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