Condition
Leptomeningeal Disease (LMD) clinical trials and research
As of November 12, 2026, Find a Trial lists 2 Leptomeningeal Disease (LMD) clinical trials that are recruiting, at sites in 2 countries (most in Canada (1), United States (1)). By phase: Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 2Clinical trials
- 2Countries
All recruiting trials (2)
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SX-682 with proton craniospinal irradiation for leptomeningeal disease
This study tests whether adding SX-682 to proton craniospinal irradiation can be safe and helpful for adults with leptomeningeal disease from melanoma or NSCLC.
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Spinal fluid and blood liquid biopsy for people with metastatic solid tumors with or without brain involvement
This will test whether a one-time spinal fluid (CSF) and blood sample can find tumor DNA in people with metastatic solid tumors, including those with brain metastases or leptomeningeal disease.
Related topics
Quick answers
How many Leptomeningeal Disease (LMD) clinical trials are recruiting right now?
2, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in Canada (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.