Condition

Klinefelter Syndrome clinical trials and research

• 4Clinical trials
• 4Countries

Newest Klinefelter Syndrome clinical trials

All recruiting trials (4)

• Testosterone treatment for boys with Klinefelter syndrome during puberty

  This study tests if giving testosterone gel to boys aged 10-14 with Klinefelter syndrome can help improve their growth, body health, and brain development during puberty.

  Recruiting Phase 4 Copenhagen University Hospital, Rigshospitalet · Copenhagen · NCT06294990

• Balancing sex hormones to improve health in men with Klinefelter syndrome

  This study is testing if a new hormone treatment can improve health and sperm production in men with Klinefelter syndrome by balancing their sex hormones and looking at weight loss effects.

  Recruiting Phase 3 University of Lausanne Hospitals · Lausanne · NCT05586802

• Evaluating thyroid function and structure in Klinefelter syndrome

  This study is testing how well the thyroid works and looks in people with Klinefelter syndrome compared to healthy individuals and those with a specific thyroid condition.

  Recruiting University of Roma La Sapienza · Roma · NCT05581147

• Research on health and development in infants with sex chromosome trisomy

  This study looks at the health and development of infants with sex chromosome trisomies, like Klinefelter syndrome, to see how they grow and what early signs can help doctors provide better care.

  Recruiting at 2 sites University of Colorado, Denver · Aurora, Colorado and 1 other locations · NCT03396562

Related topics

Quick answers

How many Klinefelter Syndrome clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in Denmark (1 trial), Italy (1 trial), United States (1 trial), Switzerland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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