Condition
IBS-D (Diarrhea-predominant) clinical trials and research
As of November 12, 2026, Find a Trial lists 3 IBS-D (Diarrhea-predominant) clinical trials that are recruiting, at sites in 4 countries (most in Hungary (1), Portugal (1), Spain (1)). 1 was first registered in the last 30 days. By phase: Phase 3 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 1New in 30 days
- 4Countries
Newest IBS-D (Diarrhea-predominant) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Probiotic in IBS-D and functional diarrhea (three-month test) | — | Szeged | Recruiting | Nov 4, 2026 |
| Saccharomyces boulardii probiotic for non-constipated IBS (diarrhea or mixed) | Phase 3 | Braga and 9 other locations | Recruiting | Sep 11, 2025 |
| Rifaximin plus N-acetylcysteine (NAC) for diarrhea-predominant IBS | Phase 2 | Los Angeles, California | Recruiting | Dec 10, 2024 |
All recruiting trials (3)
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Probiotic in IBS-D and functional diarrhea (three-month test)
A probiotic capsule is being tested to see if it can improve symptoms and quality of life for adults with diarrhea-predominant IBS or functional diarrhea compared with a placebo.
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Saccharomyces boulardii probiotic for non-constipated IBS (diarrhea or mixed)
This trial will test whether the probiotic Saccharomyces boulardii CNCM I-745 reduces overall symptoms in adults (18–65) with non-constipated IBS compared with placebo after 8 weeks.
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Rifaximin plus N-acetylcysteine (NAC) for diarrhea-predominant IBS
This study will see if adding the supplement N-acetylcysteine (NAC) to rifaximin helps adults with IBS-D have less belly pain and firmer stools.
Related topics
Quick answers
How many IBS-D (Diarrhea-predominant) clinical trials are recruiting right now?
3, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in Hungary (1 trial), Portugal (1 trial), Spain (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.