Condition
Hypogammaglobulinemia clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Hypogammaglobulinemia clinical trials that are recruiting, at sites in 14 countries (most in United States (3), Bulgaria (2), Poland (2)). By phase: Phase 3 (2), Phase 2 (1), Phase 2/3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 14Countries
Newest Hypogammaglobulinemia clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Panzyga to prevent major infections during autoimmune therapy | Phase 3 | Glendale, Arizona and 24 other locations | Recruiting | Oct 24, 2025 |
| Using IgPro20 to prevent infections in patients with multiple myeloma and low immunoglobulin levels | Phase 2 | Atlanta, Georgia and 8 other locations | Recruiting | May 16, 2025 |
| Testing if stopping immunoglobulin therapy and using antibiotics can prevent infections in blood cancer patients | Phase 2/3 | Garran, Australian Capital Territory and 6 other locations | Recruiting | Jan 10, 2023 |
| Evaluating XEMBIFY® with standard treatment to prevent infections in patients with certain blood cancers | Phase 3 | Bullhead City, Arizona and 61 other locations | Recruiting | Dec 9, 2022 |
| Exploring the link between immunoglobulin deficiency and fatigue in multiple sclerosis patients | — | Bern, Canton of Bern | Recruiting | May 3, 2022 |
All recruiting trials (5)
-
Panzyga to prevent major infections during autoimmune therapy
This Phase 3 trial tests whether Panzyga can help prevent serious infections in adults with hypogammaglobulinemia who are receiving B-cell depletion therapy for autoimmune or rheumatic conditions.
-
Using IgPro20 to prevent infections in patients with multiple myeloma and low immunoglobulin levels
This study is testing if IgPro20 can help prevent infections in people with multiple myeloma and low immune levels who are receiving certain treatments.
-
Testing if stopping immunoglobulin therapy and using antibiotics can prevent infections in blood cancer patients
This study is testing if blood cancer patients can safely stop their immunoglobulin therapy after six months and use antibiotics instead to prevent infections.
-
Evaluating XEMBIFY® with standard treatment to prevent infections in patients with certain blood cancers
This study is testing if adding XEMBIFY® to standard treatment can help prevent serious infections in adults with certain blood cancers.
-
Exploring the link between immunoglobulin deficiency and fatigue in multiple sclerosis patients
This study is trying to see if low levels of a certain antibody in people with multiple sclerosis can be a cause of their fatigue and if treating it could help them feel better.
Related topics
Quick answers
How many Hypogammaglobulinemia clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 14 countries. The most sites are in United States (3 trials), Bulgaria (2 trials), Poland (2 trials), Bosnia and Herzegovina (1 trial), Croatia (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 3: 2, Phase 2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.