Condition

Hypercholesterolaemia clinical trials and research

• 8Clinical trials
• 16Countries

Newest Hypercholesterolaemia clinical trials

All recruiting trials (8)

• Linking social care with healthcare to help manage chronic diseases

  This trial tests whether pairing patients with trained community health workers can help them get transportation, healthy food, information, and better access to care to improve health in conditions like hypertension, diabetes, and high cholesterol.

  Recruiting at 2 sites University of Arizona · Tucson, Arizona and 1 other locations · NCT07799961

• A new combination pill to lower LDL cholesterol in adults who haven’t taken cholesterol medicine before

  This study tests whether a fixed-dose combo pill of laroprovstat and rosuvastatin can lower LDL-C better than laroprovstat alone, rosuvastatin alone, or placebo in adults without prior lipid therapy.

  Recruiting at 12 sites Phase 3 AstraZeneca · Dothan, Alabama and 151 other locations · NCT07619131

• Fixed-dose combination of laroprovstat/rosuvastatin vs rosuvastatin alone for high cholesterol

  This study tests whether a fixed-dose combo pill of laroprovstat and rosuvastatin lowers LDL cholesterol better than rosuvastatin alone in adults with high cholesterol who have or are at risk for cardiovascular disease.

  Recruiting at 16 sites Phase 3 AstraZeneca · Sun City West, Arizona and 44 other locations · NCT07619118

• Obicetrapib vs. bempedoic acid for high-risk high cholesterol patients

  This phase 3 study tests whether obicetrapib can lower LDL-C more than bempedoic acid in adults with primary non-familial hypercholesterolemia or mixed dyslipidemia who still have high LDL-C despite maximum tolerated therapy.

  Recruiting Phase 3 A. Menarini International Licensing S.A. · Stockton-on-Tees · NCT07614958

• Combination therapy with QCZ484 and Inclisiran for hypertension with high cholesterol

  This study tests whether the drug QCZ484, alone or with Inclisiran, lowers cholesterol and helps blood pressure in adults with hypertension and high cholesterol.

  Recruiting at 29 sites Phase 2 Novartis · Foley, Alabama and 28 other locations · NCT07610278

• CTX310 for refractory high triglycerides or LDL cholesterol

  This trial will test whether a single IV dose of CTX310 is safe and tolerated in adults whose high triglycerides or LDL cholesterol have not responded to available treatments.

  Recruiting at 16 sites Phase 1 CRISPR Therapeutics · Hialeah, Florida and 16 other locations · NCT07491172

• Adherence, persistence, and real-life effectiveness of alirocumab 300 mg for people with high cholesterol in Italy

  This project will test whether alirocumab 300 mg helps people with high cholesterol in Italy stick with their treatment and lower their cholesterol when used in routine care.

  Recruiting Federico II University · Naples, Napoli · NCT07375225

• Evaluating the impact of inclisiran on lowering LDL cholesterol in patients after acute cardiovascular events

  This study is testing if adding a new cholesterol-lowering medication called inclisiran to regular care can help people who have recently had a heart attack or stroke lower their LDL cholesterol levels better than just regular care alone.

  Recruiting at 10 sites Phase 4 Novartis · Corrientes and 10 other locations · NCT06501443

Related topics

Quick answers

How many Hypercholesterolaemia clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (5 trials), United Kingdom (3 trials), Australia (2 trials), Canada (2 trials), Germany (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 3, Phase 2: 1, Phase 1: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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