Condition
High-grade B-cell Lymphoma (HGBCL) clinical trials and research
As of November 12, 2026, Find a Trial lists 4 High-grade B-cell Lymphoma (HGBCL) clinical trials that are recruiting, at sites in 5 countries (most in Italy (1), Canada (1), United States (1)). By phase: Phase 2 (2), Phase 2/3 (1), Phase 1 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 5Countries
Newest High-grade B-cell Lymphoma (HGBCL) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| NexCAR19 (Talikabtagene Autoleucel) for relapsed or refractory B‑cell leukemias and lymphomas | Phase 2/3 | Ankara and 3 other locations | Recruiting | Mar 30, 2026 |
| Treatment with Loncastuximab Tesirine for Lymphoma After CAR-T Therapy Failure | Phase 2 | Alessandria, ALESSANDRIA and 6 other locations | Recruiting | Apr 9, 2025 |
| Evaluating GF-CART01 for treating relapsed or refractory B-cell cancers | Phase 1 | Taipei | Recruiting | Nov 25, 2024 |
| CAR-T cell therapy for relapsed or refractory DLBCL | Phase 2 | Birmingham, Alabama and 31 other locations | Recruiting | Mar 11, 2021 |
All recruiting trials (4)
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NexCAR19 (Talikabtagene Autoleucel) for relapsed or refractory B‑cell leukemias and lymphomas
This trial will test modified versions of a patient's own T cells (NexCAR19/Talikabtagene Autoleucel) to see if they can control relapsed or refractory B‑cell leukemias and lymphomas in adults.
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Treatment with Loncastuximab Tesirine for Lymphoma After CAR-T Therapy Failure
This study is testing if a new treatment called Loncastuximab Tesirine can help people with lymphoma who didn't get better after CAR-T therapy.
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Evaluating GF-CART01 for treating relapsed or refractory B-cell cancers
This study is testing a new CAR T cell therapy called GF-CART01 to see if it can help adults with tough-to-treat B-cell cancers that haven't responded to other treatments.
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CAR-T cell therapy for relapsed or refractory DLBCL
This study is testing a new CAR-T cell therapy to see if it can help people with tough-to-treat diffuse large B cell lymphoma feel better after other treatments haven’t worked.
Related topics
Quick answers
How many High-grade B-cell Lymphoma (HGBCL) clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in Italy (1 trial), Canada (1 trial), United States (1 trial), Turkey (Türkiye) (1 trial), Taiwan (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 2/3: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.