Condition
First-line Treatment clinical trials and research
As of November 12, 2026, Find a Trial lists 5 First-line Treatment clinical trials that are recruiting, at sites in 4 countries (most in China (2), Germany (1), Norway (1)). By phase: Phase 1 (2), Phase 2 (2), Phase 3 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 4Countries
Newest First-line Treatment clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| SAR445877 with FOLFOX6 and bevacizumab as first-line treatment for MSS metastatic colorectal cancer | Phase 1 | Houston, Texas | Recruiting | Mar 30, 2026 |
| Paclitaxel liver-artery infusion plus standard chemo for first-line colorectal liver metastases | Phase 1 | Lishui, Zhejiang | Recruiting | Aug 12, 2025 |
| Cemiplimab as first-line treatment for advanced basal cell carcinoma | Phase 2 | Erfurt and 7 other locations | Recruiting | May 20, 2025 |
| Using precision medicine to choose chemotherapy for metastatic colorectal cancer | Phase 2 | Trondheim | Recruiting | Apr 2, 2025 |
| Comparing disitamab vedotin and pyrotinib to standard treatment for HER2-positive advanced breast cancer | Phase 3 | Guangzhou, Guangdong | Recruiting | Feb 26, 2024 |
All recruiting trials (5)
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SAR445877 with FOLFOX6 and bevacizumab as first-line treatment for MSS metastatic colorectal cancer
This study tests whether giving SAR445877 together with FOLFOX6 and bevacizumab is safe and tolerable as a first-line treatment for adults with MSS metastatic colorectal cancer.
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Paclitaxel liver-artery infusion plus standard chemo for first-line colorectal liver metastases
This trial will see if giving paclitaxel cationic liposome into the liver artery together with standard first-line chemotherapy (oxaliplatin and capecitabine, with or without bevacizumab) helps people with inoperable colorectal liver metastases.
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Cemiplimab as first-line treatment for advanced basal cell carcinoma
This trial will try cemiplimab as a first-line treatment for adults with locally advanced basal cell carcinoma who have not received hedgehog inhibitors.
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Using precision medicine to choose chemotherapy for metastatic colorectal cancer
This study is testing whether a new way to choose the best chemotherapy for people with metastatic colorectal cancer can help them live longer and feel better.
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Comparing disitamab vedotin and pyrotinib to standard treatment for HER2-positive advanced breast cancer
This study is testing a new combination of disitamab vedotin and pyrotinib to see if it works better than the standard treatment for people with newly diagnosed HER2-positive advanced breast cancer.
Related topics
Quick answers
How many First-line Treatment clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 4 countries. The most sites are in China (2 trials), Germany (1 trial), Norway (1 trial), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1: 2, Phase 2: 2, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.