Condition

Essential Thrombocythemia clinical trials and research

• 15Clinical trials
• 24Countries

Newest Essential Thrombocythemia clinical trials

All recruiting trials (15)

• A Phase 3 Test of INCA033989 vs Best Available Therapy for Essential Thrombocythemia with CALR Mutation

  This phase 3 study tests whether INCA033989 can help people with essential thrombocythemia who have a CALR mutation and have already had cytoreductive therapy, compared to the best available treatment.

  Recruiting at 5 sites Phase 3 Incyte Corporation · Birmingham, Alabama and 191 other locations · NCT07623200

• Evaluating Peginterferon for treating Essential Thrombocythemia and Polycythemia Vera

  This study is testing if a weekly injection of Peginterferon can help people with Essential Thrombocythemia and Polycythemia Vera feel better and stay safe while using the treatment.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06734637

• Comparing ASTX727 with and without Iadademstat for advanced blood cancers

  This study is testing whether adding iadademstat to the ASTX727 treatment can help people with advanced blood cancers feel better and live longer compared to just using ASTX727 alone.

  Recruiting at 32 sites Phase 2 National Cancer Institute (NCI) · Irvine, California and 31 other locations · NCT06661915

• Peginterferon α-2b for patients with resistant or intolerant Essential Thrombocythemia

  This study is testing if a new medication called Peginterferon α-2b can help people with essential thrombocythemia who haven't had success with or can't tolerate their current treatment.

  Recruiting at 8 sites Phase 2 Xiamen Amoytop Biotech Co., Ltd. · Beijing and 7 other locations · NCT06552429

• Evaluating GLB-001 for patients with myeloid malignancies

  This study is testing a new oral treatment called GLB-001 to see if it is safe and effective for people with certain types of blood cancers that have come back or didn't respond to other treatments.

  Recruiting at 14 sites Phase 1 Hangzhou GluBio Pharmaceutical Co., Ltd. · Hefei, Anhui and 13 other locations · NCT06378437

• Characterizing Monocytes in Blood Disorders

  This study is trying to learn more about the role of certain blood cells called monocytes in patients with specific blood disorders to see how they might affect the disease and treatment options.

  Recruiting University Hospital, Angers · Angers, Maine et Loire and 2 other locations · NCT06361641

• Curcumin for treating inflammation and symptoms in blood disorders

  This study is testing if a curcumin supplement can help reduce inflammation and improve symptoms in people with certain blood disorders.

  Recruiting at 2 sites Phase 2 University of Southern California · Los Angeles, California and 1 other locations · NCT06063486

• Registry of Asian patients with myeloproliferative neoplasms

  This study is collecting information from Asian patients with myeloproliferative neoplasms to learn more about their condition and how different treatments work for them.

  Recruiting The University of Hong Kong · Hong Kong · NCT05882773

• Comparing Apixaban and Rivaroxaban to Aspirin for Preventing Blood Clots in Certain Blood Disorders

  This study is testing whether the blood thinners Apixaban and Rivaroxaban can prevent blood clots better than low-dose aspirin in patients with certain blood disorders who are at high risk.

  Recruiting at 20 sites Phase 3 University Hospital, Brest · Angers and 41 other locations · NCT05198960

• Finding the best dose of N-Acetylcysteine for patients with blood disorders

  This study is testing the best dose of N-Acetylcysteine to see if it can help people with certain blood disorders feel better while they continue their usual treatments.

  Recruiting Phase 1/2 University of California, Irvine · Irvine, California and 1 other locations · NCT05123365

• Reduced-intensity conditioning to lower treatment-related mortality in stem cell transplant patients

  This study is testing a new way to prepare patients for a stem cell transplant to see if it can lower the risk of serious treatment-related complications.

  Recruiting Phase 2 Thomas Jefferson University · Philadephia, Pennsylvania · NCT05031897

• Evaluating CALR Allele Burden in Myeloproliferative Neoplasms

  This study is trying to see if tracking a specific genetic change in the blood can help doctors understand how myeloproliferative neoplasms progress in patients over time.

  Recruiting at 10 sites University Hospital, Angers · Angers and 9 other locations · NCT04942080

• Using Ruxolitinib to treat symptoms of essential thrombocythemia and polycythemia vera

  This study is testing if the drug Ruxolitinib can help reduce symptoms for people with low-risk essential thrombocythemia and polycythemia vera.

  Recruiting at 3 sites Phase 2 Massachusetts General Hospital · Boston, Massachusetts and 3 other locations · NCT04644211

• Combining decitabine with ruxolitinib, fedratinib, or pacritinib for treating advanced myeloproliferative neoplasms

  This study is testing if combining decitabine with other medications can help patients with advanced blood cancers get ready for a stem cell transplant.

  Recruiting Phase 2 University of Washington · Seattle, Washington · NCT04282187

• Registry for patients with myeloproliferative neoplasms

  This study is creating a database to gather information from people with myeloproliferative neoplasms to help improve treatments and outcomes for these rare blood cancers.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT02760238

Related topics

Quick answers

How many Essential Thrombocythemia clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (7 trials), France (4 trials), China (3 trials), Canada (2 trials), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 3: 2, Phase 1/2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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