Condition

Disc Degeneration clinical trials and research

• 5Clinical trials
• 5Countries

Newest Disc Degeneration clinical trials

All recruiting trials (5)

• Two-Level Spinal Fusion for Disc Degeneration or Deformity: MDT-0123 compared with Autologous Bone Graft

  This study tests MDT-0123 against the patient’s own bone graft to see which helps two-level spine fusion better in people with disc degeneration or spinal deformity.

  Recruiting at 14 sites Phase 3 Medtronic Spinal and Biologics · Kobe, Hyōgo and 13 other locations · NCT07414745

• Comparing two bioactive bone substitutes to help spinal fusion after anterior lumbar surgery

  This trial tests two osteoinductive bioactive bone substitutes to see which better helps adults with degenerative lumbar disc disease achieve spinal fusion after anterior lumbar interbody surgery.

  Recruiting University Hospital, Montpellier · Montpellier, France · NCT07044206

• Evaluating a new treatment for painful disc degeneration

  This study is testing a new non-surgical treatment for people with painful disc degeneration to see if it can help relieve their back pain when other treatments haven't worked.

  Recruiting at 19 sites VIVEX Biologics, Inc. · Napa, California and 18 other locations · NCT06778447

• Preoperative IV dexamethasone to reduce pain after minimally invasive lumbar fusion (MIS-TLIF)

  This trial will test whether a single intravenous dose of dexamethasone given before MIS-TLIF reduces postoperative back pain and opioid use in people aged 50–80 having 1–2 level lumbar fusion.

  Recruiting Phase 4 Thammasat University Hospital · Pathum Thani, Changwat Pathum Thani · NCT06367855

• Using ZetaFuse Bone Graft to treat cervical disc disease

  This study is testing if a new bone graft called ZetaFuse can help people with neck problems feel better and improve their nerve function after surgery.

  Recruiting at 2 sites Zetagen Therapeutics, Inc · Randwick, New South Wales and 1 other locations · NCT05971329

Related topics

Quick answers

How many Disc Degeneration clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in France (1 trial), Australia (1 trial), Japan (1 trial), United States (1 trial), Thailand (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →