Condition

Chronic Lymphocytic Leukaemia clinical trials and research

• 5Clinical trials
• 25Countries

Newest Chronic Lymphocytic Leukaemia clinical trials

All recruiting trials (5)

• MK-1045-006: testing a new treatment for B-cell cancers like CLL and SLL

  This trial will test MK-1045 in people with relapsed or treatment‑refractory CLL/SLL to see if it’s safe and how well it works.

  Recruiting at 8 sites Phase 2 Merck Sharp & Dohme LLC · Medellín, Antioquia and 7 other locations · NCT07709000

• Acalabrutinib treatment for patients with chronic lymphocytic leukaemia and heart failure

  This study is testing if a new drug called acalabrutinib is safe and effective for people with chronic lymphocytic leukaemia and heart failure compared to other treatment options.

  Recruiting at 18 sites Phase 4 AstraZeneca · Charlotte, North Carolina and 22 other locations · NCT06651970

• Evaluating AZD0486 for treating mature B-cell cancers

  This study is testing a new treatment called AZD0486 to see if it can help people with certain types of mature B-cell cancers feel better and improve their health.

  Recruiting at 56 sites Phase 1/2 AstraZeneca · Boston, Massachusetts and 65 other locations · NCT06564038

• Testing tumor samples from patients with second cancers after gene therapy

  This study is testing tumor samples from patients who have had gene therapy to see if there's a link between the treatment and the development of a second cancer.

  Recruiting at 5 sites Bristol-Myers Squibb · Portland, Oregon and 7 other locations · NCT06357754

• Evaluating the effects of nemtabrutinib in patients with blood cancers

  This study is testing a new oral medication called nemtabrutinib to see if it can help people with blood cancers like chronic lymphocytic leukemia and Waldenström's macroglobulinemia feel better and stay safe.

  Recruiting at 94 sites Phase 2 Merck Sharp & Dohme LLC · Springdale, Arkansas and 120 other locations · NCT04728893

Related topics

Quick answers

How many Chronic Lymphocytic Leukaemia clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 25 countries. The most sites are in Spain (4 trials), United States (4 trials), Czechia (3 trials), Germany (3 trials), Italy (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 4: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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