Condition

BRAF V600E Mutation Positive clinical trials and research

• 4Clinical trials
• 2Countries

Newest BRAF V600E Mutation Positive clinical trials

All recruiting trials (4)

• Neoadjuvant therapy with encorafenib plus cetuximab N01 and mFOLFOX6 in locally advanced BRAF V600E-mutant colorectal cancer

  This trial tests a targeted, pre-surgery treatment to see if it improves the chance of long-term control in adults with locally advanced BRAF V600E-mutant colorectal cancer.

  Recruiting Phase 2 Zhejiang University · Hangzhou, Zhejiang · NCT07789210

• Neoadjuvant targeted therapy for ameloblastoma

  This study is testing if a new targeted therapy can help patients with a specific type of jaw tumor called ameloblastoma have less invasive surgery instead of more extensive surgery.

  Recruiting Phase 2 Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · Shanghai, Shanghai Municipality · NCT06653517

• Combination treatment for localized colon or upper rectum cancer with BRAF mutation

  This study is testing a combination treatment of encorafenib and cetuximab for patients with localized colon or upper rectal cancer that has a specific BRAF mutation to see if it helps before surgery.

  Recruiting Phase 2 Federation Francophone de Cancerologie Digestive · Paris · NCT05706779

• Collecting data from patients with BRAFV600E-mutated metastatic colorectal cancer

  This study is collecting information and samples from patients with a specific type of metastatic colorectal cancer to see how well different treatments work and what factors affect their outcomes.

  Recruiting at 27 sites Unicancer · Avignon and 44 other locations · NCT05639413

Related topics

Quick answers

How many BRAF V600E Mutation Positive clinical trials are recruiting right now?

4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in France (2 trials), China (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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