Condition

Antiphospholipid Syndrome (APS) clinical trials and research

• 8Clinical trials
• 22Countries

Newest Antiphospholipid Syndrome (APS) clinical trials

All recruiting trials (8)

• Anifrolumab for adults with primary antiphospholipid syndrome

  This phase II pilot tests whether weekly subcutaneous anifrolumab is safe and tolerable in adults with primary antiphospholipid syndrome while they continue their standard care.

  Recruiting Phase 2 National and Kapodistrian University of Athens · Athens, Greece · NCT07584083

• DOACs versus VKAs to prevent repeat clots in low‑risk antiphospholipid syndrome

  This project will see if direct oral anticoagulants (DOACs) work as well and are as safe as vitamin K antagonists (VKAs) to prevent repeat venous clots in adults with low‑risk thrombotic antiphospholipid syndrome.

  Recruiting at 2 sites Infanta Leonor University Hospital · Madrid, Madrid and 1 other locations · NCT07372170

• Long-term follow-up of adults with antiphospholipid syndrome

  This project will test how often blood clots come back and which factors affect recurrence in adults with antiphospholipid syndrome.

  Recruiting University Hospital, Rouen · Rouen · NCT07178925

• YTS109 cell therapy for relapsed/refractory autoimmune diseases

  This trial will try a single infusion of YTS109 immune cells to see if they are safe and help adults aged 18–65 with relapsed or refractory autoimmune diseases such as lupus, Sjogren’s syndrome, inflammatory myopathy, or ANCA-associated vasculitis.

  Recruiting Phase 1 China Immunotech (Beijing) Biotechnology Co., Ltd. · Tianjin · NCT07123519

• YTS109 cell therapy for relapsed or refractory autoimmune diseases

  This trial will try a single infusion of YTS109 cells to see if they are safe and help adults (18–65) with relapsing or refractory autoimmune diseases such as SLE, lupus nephritis, systemic sclerosis, inflammatory myopathy, or ANCA-associated vasculitis.

  Recruiting Phase 1 China Immunotech (Beijing) Biotechnology Co., Ltd. · Hefei, Anhui · NCT07104721

• YTS109 cell therapy for relapsed or refractory systemic autoimmune diseases

  This trial will try a single infusion of YTS109 cells to see if it's safe and helps adults 18–65 with relapsed or refractory systemic autoimmune diseases such as SLE, systemic sclerosis, inflammatory myopathies, ANCA-associated vasculitis, or antiphospholipid syndrome.

  Recruiting Phase 1 China Immunotech (Beijing) Biotechnology Co., Ltd. · Beijing, Beijing Municipality · NCT06978647

• Evaluating Belimumab's effect on antibody levels in patients with Antiphospholipid Syndrome

  This study is testing if adding Belimumab to standard treatment can lower antibody levels in people with Antiphospholipid Syndrome.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, Shanghai Municipality · NCT06747312

• Testing RAY121 for various immunological diseases

  This study is testing a new drug called RAY121 to see if it can safely help people with different immune system diseases like antiphospholipid syndrome and dermatomyositis.

  Recruiting at 48 sites Phase 1 Chugai Pharmaceutical · Orange, California and 76 other locations · NCT06371417

Related topics

Quick answers

How many Antiphospholipid Syndrome (APS) clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 22 countries. The most sites are in China (4 trials), France (2 trials), Spain (2 trials), Australia (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 4, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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