Drug or treatment

Belimumab clinical trials

• 16Clinical trials
• 21Countries

Newest trials

All recruiting trials (16)

• LUPKYNIS in combination with belimumab, obinutuzumab, or anifrolumab for lupus nephritis

  This trial tests whether adding LUPKYNIS to other biologics (belimumab, obinutuzumab, or anifrolumab) plus a mycophenolic acid analog and a steroid can rapidly improve kidney health in adults with biopsy-proven lupus nephritis.

  Recruiting at 27 sites Phase 4 Aurinia Pharmaceuticals Inc. · La Mesa, California and 26 other locations · NCT07611214

• Belimumab to mobilize memory B cells to help delistings for highly sensitized kidney transplant candidates

  A short belimumab course is being tested to see if it can reveal memory B cells that target donor HLAs, helping to decide which donors to exclude and potentially speed up getting a transplant for highly sensitized patients.

  Recruiting Phase 2 Leiden University Medical Center · Leiden · NCT07539857

• Comparing two biologic induction regimens and standard mycophenolate therapy for active proliferative lupus nephritis over six months

  This trial will test whether biologic induction therapy with belimumab or telitacicept leads to better kidney responses over six months than standard mycophenolate-based treatment in people aged 14–65 with active proliferative lupus nephritis.

  Recruiting Phase 2 Nanjing University School of Medicine · Nanjing, Jiangsu · NCT07340463

• Combining belimumab and voclosporin for proliferative lupus kidney disease

  This trial will test whether giving belimumab and voclosporin together with background mycophenolate helps people with proliferative lupus nephritis reach complete kidney remission and lets doctors stop mycophenolate sooner.

  Recruiting at 7 sites Phase 4 NephroNet, Inc. · Glendale, Arizona and 6 other locations · NCT07225387

• Belimumab and the long-term course of lupus

  This study will see if belimumab lowers the risk of new major organ flares in adults with active systemic lupus compared with standard care.

  Recruiting Biomedical Research Foundation, Academy of Athens · Athens, Attica · NCT07056621

• Evaluating Belimumab's effect on antibody levels in patients with Antiphospholipid Syndrome

  This study is testing if adding Belimumab to standard treatment can lower antibody levels in people with Antiphospholipid Syndrome.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, Shanghai Municipality · NCT06747312

• Investigating the long-term effects of Belimumab in adults with lung disease related to systemic sclerosis

  This study is testing if the medication Belimumab can help adults with lung disease related to systemic sclerosis feel better and slow down their disease over the long term.

  Recruiting at 41 sites Phase 3 GlaxoSmithKline · Los Angeles, California and 40 other locations · NCT06716606

• Evaluating Belimumab for Lung Disease Linked to Autoimmune Conditions

  This study is testing if the medication belimumab can help adults with lung disease caused by autoimmune conditions feel better and breathe easier.

  Recruiting at 126 sites Phase 3 GlaxoSmithKline · Los Angeles, California and 131 other locations · NCT06572384

• Assessing the effectiveness of belimumab for lupus nephritis treatment

  This study is testing how well belimumab works for adults with active lupus nephritis to see if it helps protect their kidney function over time.

  Recruiting at 7 sites GlaxoSmithKline · Baltimore, Maryland and 6 other locations · NCT06527872

• Using belimumab after rituximab for treating resistant juvenile Sjogren's syndrome

  This study is testing if giving belimumab after rituximab can help children aged 5-18 with tough-to-treat juvenile Sjogren's syndrome feel better.

  Recruiting Phase 4 Peking Union Medical College Hospital · Beijing, Beijing Municipality · NCT06410833

• Using Belimumab to treat Autoimmune Hepatitis

  This study is testing if Belimumab can help people with autoimmune hepatitis feel better and improve their liver function when other treatments haven't worked.

  Recruiting at 6 sites Phase 2 University Health Network, Toronto · Calgary, Alberta and 5 other locations · NCT06381453

• Evaluating belimumab for treating lung disease in systemic sclerosis

  This study is testing if belimumab can help improve lung function and overall quality of life for adults with lung disease caused by systemic sclerosis.

  Recruiting at 114 sites Phase 2/3 GlaxoSmithKline · Phoenix, Arizona and 133 other locations · NCT05878717

• Combining Belimumab with Rituximab for Chronic Immune Thrombocytopenia

  This study is testing if a new combination of two medications can help adults with chronic immune thrombocytopenia raise their platelet counts after other treatments have stopped working.

  Recruiting Phase 3 Assistance Publique - Hôpitaux de Paris · Créteil · NCT05338190

• Evaluating the safety of belimumab for people with low CD4 cell counts and autoantibodies

  This study is testing if belimumab is safe for adults with low CD4 cell counts and autoantibodies to see if it could be a new treatment option for their condition.

  Recruiting Phase 1 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04097561

• Combining belimumab and rituximab for treating primary membranous nephropathy

  This study is testing if combining two medications, belimumab and rituximab, can help adults with primary membranous nephropathy feel better and achieve remission more effectively than using rituximab alone.

  Recruiting at 20 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Birmingham, Alabama and 19 other locations · NCT03949855

• Evaluating belimumab for early lupus treatment

  This study is testing if the drug belimumab can help people who have been diagnosed with lupus in the last two years feel better and possibly stay in remission.

  Recruiting Phase 4 Northwell Health · Manhasset, New York · NCT03543839

Quick answers

How many clinical trials of Belimumab are recruiting right now?

16, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 21 countries. The most sites are in United States (9 trials), China (6 trials), France (5 trials), Greece (4 trials), Japan (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 5, Phase 4: 4, Phase 3: 3, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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