Condition
Advanced Intrahepatic Cholangiocarcinoma clinical trials and research
Research outlook What's coming for Cholangiocarcinoma: the next 6 months to 5 yearsAs of November 12, 2026, Find a Trial lists 4 Advanced Intrahepatic Cholangiocarcinoma clinical trials that are recruiting, at sites in 2 countries (most in China (3), United States (1)). By phase: Phase 2 (2), Phase 2/3 (1), Phase 1/2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 4Clinical trials
- 2Countries
Newest Advanced Intrahepatic Cholangiocarcinoma clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Personalized mRNA therapy for advanced liver cancer | Phase 1/2 | Hangzhou, Zhejiang | Recruiting | May 4, 2025 |
| Systemic therapy with or without targeted liver radiation for advanced intrahepatic cholangiocarcinoma | Phase 2 | Houston, Texas | Recruiting | Mar 5, 2025 |
| Treatment of advanced intrahepatic cholangiocarcinoma with VG161 | Phase 2 | Hangzhou, Zhejiang | Recruiting | Dec 24, 2024 |
| Evaluating HMPL-453 for advanced intrahepatic cholangiocarcinoma | Phase 2/3 | Beijing, Beijing Municipality | Recruiting | Apr 20, 2020 |
All recruiting trials (4)
-
Personalized mRNA therapy for advanced liver cancer
This study is testing a personalized mRNA therapy combined with standard chemotherapy to see if it can help people with advanced liver cancer feel better.
-
Systemic therapy with or without targeted liver radiation for advanced intrahepatic cholangiocarcinoma
This trial tests whether adding liver-directed radiation to standard chemotherapy plus durvalumab helps people with advanced intrahepatic cholangiocarcinoma live longer.
-
Treatment of advanced intrahepatic cholangiocarcinoma with VG161
This study is testing a new injectable treatment called VG161 for people with advanced bile duct cancer who haven't had success with other therapies to see if it can help shrink their tumors.
-
Evaluating HMPL-453 for advanced intrahepatic cholangiocarcinoma
This study is testing a new drug called HMPL-453 to see if it helps people with advanced bile duct cancer that has specific genetic changes.
Related topics
Quick answers
How many Advanced Intrahepatic Cholangiocarcinoma clinical trials are recruiting right now?
4, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (3 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 2, Phase 2/3: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.