Yoga-based group intervention for in-patients with schizophrenia spectrum disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of a yoga-based group intervention (YoGI) for in-patients diagnosed with schizophrenia spectrum disorders. Participants will engage in YoGI alongside their usual psychiatric treatment, with assessments conducted before and after the intervention period to measure outcomes. The study employs a rater-blinded randomized controlled design to ensure unbiased results, focusing on the primary outcome of positive symptoms as measured by the Positive and Negative Syndrome Scale (PANSS). Saliva samples will also be collected to analyze stress-related biomarkers, contributing to a comprehensive understanding of the intervention's impact.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* male and female participants
* treated as psychiatric inpatients at the psychosis ward or in the social-psychiatric day clinic
* ≥18 years
* diagnosis of a schizophrenia-spectrum disorder according to the Diagnostical and Statistical Manual 5th edition) and the International Statistical Classification of Diseases and Related Health Problems(ICD-10) code F2
* ability to give informed consent
* willingness and ability to engage in psychotherapeutic group therapy
* low to moderate psychotic state indicated with a score of ≤ 6 for each item at the Positive scale of the Positive and Negative Syndrome Scale (PANSS, Peralta \& Cuesta, 1994)

Exclusion Criteria:

* a score \> 6, suggesting an acute psychotic episode with severe psychotic symptoms (Peralta\& Cuesta, 1994)
* acute suicidality, assessed by item eight of the Calgary Depression Scale for Schizophrenia \> 1 (Addington, Addington, Maticka-Tyndale, \& Joyce, 1992)
* any neurological disorders that may affect cognitive functioning
* acute substance abuse other than nicotine and prescribed medication
* conflicting co-therapy such as electroconvulsive therapy or ketamine treatment

Where it's running

• Charité Universitätsmedizin Berlin, Campus Benjamin Franklin
  Steglitz, State of Berlin, Germany Recruiting

Study contacts

• Study coordinator: Kerem Böge, Dr.
• Email: Kerem.boege@charite.de
• Phone: 0049 30 450 517 789

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.