Whole-body MRI for non-invasive lesion detection and therapy follow-up in radiographic and non-radiographic axial spondyloarthritis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational cohort using whole-body MRI (WB-MRI) to image multiple body regions in patients with suspected axial spondyloarthritis and to follow them over time. Imaging features from WB-MRI will be correlated with clinical measures of disease activity, inflammation, and structural damage. The project will apply data mining and machine-learning methods to build a WB-MRI–based disease activity model, with separate discovery and validation cohorts to test accuracy and reliability. Dynamic follow-up imaging will be used to examine how MRI findings change with therapy and clinical course.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Include newly referred patients if:

The onset of symptoms (back pain/arthritis/enthesitis) \< 45 years

Undiagnosed disease with the following symptoms:

chronic back pain (duration of back pain more than 3 months) and/or peripheral arthritis (asymmetric arthritis/predominantly of the lower limbs) and/or enthesitis and/or dactylitis

Exclusion Criteria:

And diagnosed with non-radiographic or radiographic axial SpA

Where it's running

• The First Affiliated Hospital of Nanjing Medical University
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Wenfeng Tan, Dr
• Email: tw2006@njmu.edu.cn
• Phone: +8618061202878

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.