Which fundoplication? Nissen vs Hil Snow for kids with GERD
Official title: the Effect of the Laparoscopic Management of Gastro Esophageal Reflux on Gastric Emptying in Pediatric Age Group
Run by Tanta University · NCT07708220 · Data updated 2026-11-12
In children with GERD, this trial tests two surgical options to see which one better preserves stomach emptying and reduces symptoms after anti-reflux surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 24 Months to 18 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta) |
| Status | Recruiting |
| Started | March 1, 2025 |
| Main results expected | August 1, 2026 |
| Study ends | October 1, 2026 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT07708220 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 24 months to 18 years with GERD who have not had previous anti-reflux surgery and who are eligible for fundoplication.
✕Probably not a fit
Children with complex comorbidities or contraindications to either procedure may not experience benefit from the study interventions.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective randomized trial compares Nissen fundoplication with the Hil Snow procedure in pediatric patients aged 24 months to 18 years undergoing anti-reflux surgery. Participants are assigned to one of the two surgical approaches at multiple tertiary pediatric centers. Outcomes include gastric emptying time, upper GI endoscopy findings, and post-surgical symptoms such as dysphagia, satiety, and discomfort. Data will be analyzed to identify which procedure yields better gastric function and symptom control after fundoplication.
Why it matters
Potential benefit: If successful, the study could guide surgeons toward the procedure that offers better gastric emptying and fewer digestive symptoms in children with GERD.
How similar studies have gone: Prior work in adults and pediatric surgical literature shows mixed results; this study addresses a gap with direct pediatric randomization between two techniques.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * all children with GERD above the age of 24 months until 18 years Exclusion Criteria: * previous antireflux surgery * previous exploration * Esophageal atresia congenital diaphragmatic hernia omphalocele major
Where it's running
-
Faculty of Medicine
Tanta, Egypt Recruiting
Study contacts
- Study coordinator: souzan Gado
- Email: souzan.gado@med.tanta.edu.eg
- Phone: 01010477452
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.