Which frailty tool best predicts post-op complications in older adults undergoing surgery
Official title: Evaluation of a Feasible Frailty Assessment Tool for Preoperative Risk Evaluation of Older Patients
Run by Universitätsklinikum Hamburg-Eppendorf · NCT06889545 · Data updated 2026-11-12
This study tests several frailty assessments in people 70 and older to see which best predicts postoperative problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 70 Years and up |
| Sex | All |
| Enrollment | 584 (estimated) |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf Academic / other |
| Locations | 1 site (Hamburg) |
| Status | Recruiting |
| Started | April 15, 2025 |
| Main results expected | November 1, 2027 |
| Study ends | April 1, 2028 |
| Registry record updated | July 22, 2026 |
| Trial ID | NCT06889545 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 70+ who are scheduled for surgery with an estimated duration of 120 minutes or more and who can complete cognitive testing in German.
✕Probably not a fit
Those who do not show a meaningful link between frailty test results and postoperative outcomes may have limited benefit from these assessments.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study compares multiple preoperative frailty instruments in adults aged 70 and older who are scheduled for surgery lasting at least 120 minutes. Participants will be assessed using the Risk Analysis Index, Clinical Frailty Scale, Groningen Frailty Indicator, Edmonton Frail Scale, and LUCAS-FI during the premedication visit. The goal is to determine which tool has the strongest predictive value for postoperative complications, enabling better risk stratification. The study is conducted at University Medical Centre Hamburg, led by Universitätsklinikum Hamburg-Eppendorf, with no listed collaborators. Results could inform which frailty instrument is most useful in preoperative planning for older patients.
Why it matters
Potential benefit: If a tool is identified as most predictive, clinicians can better identify high-risk patients and tailor perioperative care accordingly.
How similar studies have gone: Previous research has explored frailty tools, and some instruments show promise, but head-to-head comparisons in the preoperative setting are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 70 years and older * scheduled surgery * estimated time of surgery 120 Minutes or more Exclusion Criteria: * insufficient German language skills (for cognitive testing) * mental retardation * relevant psychiatric disorder (not allowing for cognitive testing)
Where it's running
-
University Medical Centre Hamburg
Hamburg, Germany Recruiting
Study contacts
- Principal investigator: Dr. Cynthia Olotu, MD — University Medical Centre Hamburg
- Study coordinator: Dr. Cynthia Olotu, MD
- Email: c.olotu@uke.de
- Phone: 0049 40 7410 52415
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.