Which CVC dressing securement helps prevent MARSI best
Official title: Effect of Medical Adhesive and Skin Barrier Products Used for Central Venous Catheter Dressings on the Development of Medical Adhesive-Related Skin Injury: A Randomized Controlled Trial
Run by Ege University · NCT07697430 · Data updated 2026-11-12
This study tests three dressing strategies (acrylic tape, silicone tape, and barrier film with acrylic tape) to see which best prevents MARSI in adults with central venous catheters.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 162 (estimated) |
| Sponsor | Ege University Academic / other |
| Locations | 1 site (Afyonkarahisar, Center) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | June 1, 2027 |
| Study ends | June 1, 2027 |
| Registry record updated | July 21, 2026 |
| Trial ID | NCT07697430 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18 years or older with an upcoming non-tunneled internal jugular CVC placement in the chest ICU or operating room.
✕Probably not a fit
Patients who do not develop MARSI may not experience a direct benefit beyond standard care.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this prospective, single-center study, adults requiring non-tunneled internal jugular CVCs in a chest ICU setting will be randomized to one of three dressing securement strategies. Participants will have regular skin assessments for MARSI over up to 21 days or until catheter removal. The trial aims to identify which method most effectively reduces skin injury from adhesives while maintaining catheter security. Safety and adverse skin reactions will be monitored as part of standard clinical care. Results could guide best practices for preventing MARSI in ICU patients with CVCs.
Why it matters
Potential benefit: If successful, the preferred dressing securement could reduce MARSI, improve skin integrity, and lower additional care needs and costs.
How similar studies have gone: Previous observational studies exist but high-quality comparative evidence is limited; this study seeks to provide more robust guidance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18 years or older. * Patients scheduled to undergo insertion of a non-tunneled central venous catheter via the internal jugular vein in the chest intensive care unit or operating room. * Patients who provide written informed consent to participate in the study, either personally or through their legally authorized representative. * Patients with intact skin and no pre-existing skin condition at the catheter insertion site. Exclusion Criteria: * Patients with an active or congenital dermatological disease. * Patients with a known history of allergic reactions to any of the securement products used in the study (medical adhesive tapes or protective barrier film). * Patients with clinically significant hyperhidrosis (excessive sweating). * Patients whose central venous catheter is inserted through a site other than the internal jugular vein (e.g., subclavian or femoral vein). * Patients requiring contact isolation because of an infectious disease (e.g., scabies) or airborne isolation because of a contagious disease (e.g., tuberculosis).
Where it's running
-
Afyonkarahisar Health Sciences University Health Practice and Research Center
Afyonkarahisar, Center, Turkey (Türkiye) Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.