What affects pain after taking gum grafts from the palate?
Official title: Patient-Related Factors Influencing Postoperative Pain After Gingival Graft Harvesting From the Palate: A Prospective Study
Run by Universitat Internacional de Catalunya · NCT07377370 · Data updated 2026-11-12
This project will see if patient, psychological, and clinical factors predict how much pain adults experience after having gum grafts taken from the palate.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 93 (estimated) |
| Sponsor | Universitat Internacional de Catalunya Academic / other |
| Locations | 1 site (Barcelona, Sant Cugat Del Valles) |
| Status | Recruiting |
| Started | February 2, 2026 |
| Main results expected | July 2027 |
| Study ends | September 2027 |
| Registry record updated | February 4, 2026 |
| Trial ID | NCT07377370 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are systemically healthy adults (18 years or older) who need mucogingival surgery for root coverage or soft tissue augmentation and have good periodontal health with full‑mouth plaque and bleeding scores ≤20%.
✕Probably not a fit
Patients with systemic or metabolic diseases that impair healing, heavy smokers, chronic pain disorders, psychiatric diagnoses, recent grafting, pregnancy or lactation, or regular use of interfering medications are excluded and are unlikely to benefit from this protocol's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective cohort at the Clínica Universitària d'Odontologia of Universitat Internacional de Catalunya in Barcelona will enroll consecutive adults who need mucogingival surgery for root coverage or soft tissue augmentation. All participants will receive standardized pre‑surgical periodontal care and oral hygiene instruction, and gingival grafts will be harvested from the palate under local anesthesia using a uniform surgical technique with standardized postoperative analgesics and care. Validated questionnaires will collect anticipated and postoperative pain scores plus measures of stress, dental anxiety, psychological profile, and personality traits alongside clinical healing measures. The study excludes patients with conditions or medications that impair healing or pain perception to focus on patient‑related predictors of postoperative pain.
Why it matters
Potential benefit: If successful, the results could help clinicians identify patients at higher risk of intense postoperative pain and tailor pain control and counseling after palatal graft harvesting.
How similar studies have gone: Previous observational studies have identified some clinical and psychological predictors of pain after dental surgery, but prospective, comprehensive data specifically for palatal gingival graft harvesting are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients requiring mucogingival surgery for gingival augmentation or root coverage purposes * Systemically healthy individuals aged 18 years or older * Healthy periodontal status according to the AAP/EFP definition * Full-mouth plaque score (FMPS) and full-mouth bleeding score (FMBS) ≤ 20% Exclusion Criteria: * Pregnancy or lactation * Self-reported smoking ≥10 cigarettes/day * Presence of metabolic or systemic diseases that negatively affect soft tissue healing * Use of medications that may interfere with wound healing * Chronic pain disorders (e.g., fibromyalgia) * Psychiatric diagnoses * Regular use of analgesics, antidepressants, anxiolytics, or opioids * Allergy to the study medication (Ibuprofen) * History of grafting within the past 6 months * Ongoing orthodontic therapy
Where it's running
-
Clínica Universitària d'Odontologia - UIC Barcelona
Barcelona, Sant Cugat Del Valles, Spain Recruiting
Study contacts
- Study coordinator: Lory Abrahamian, DDS, MSc, PhD Candidate
- Email: lory.abrahamian@uic.es
- Phone: +34722528012
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.