Weight management for survivors of endometrial cancer
Enacting Active Survivorship: Implementation of Weight Management Strategies in Endometrial Cancer Survivors
This study is trying to help women who have survived endometrial cancer and are struggling with obesity by offering them a weight management program that includes options like weight loss medications.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | University of Kansas Medical Center Academic / other |
| Locations | 1 site (Kansas City, Kansas) |
| Trial ID | NCT06877572 on ClinicalTrials.gov |
What this trial studies
This observational study aims to engage a multidisciplinary team to assist endometrial cancer survivors struggling with obesity in a weight management program. Participants will be referred to the KUMC OB/Gyn weight management clinic to explore weight management options, including the potential use of weight loss medications. Data will be collected from patient charts for those who opt for pharmacotherapy, while those who choose not to will have their physical exam and lab data monitored as part of routine care. The study also seeks to understand the reasons behind patients' decisions regarding weight loss medication.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a BMI of 30 kg/m2 or higher who have completed surgical staging for early-stage endometrial cancer.
Not a fit: Patients who are unable to participate in behavioral weight loss or have recent severe health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the health and longevity of endometrial cancer survivors by effectively managing obesity.
How similar studies have performed: Other studies have shown success in weight management interventions for cancer survivors, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥18 years old * ECOG 0-2 * BMI ≥ 30kg/m2 * Completed surgical staging with no evidence of residual disease * Endometrioid endometrial adenocarcinoma, p53 wild type * Stage 1 * Undergoing active surveillance +/- brachytherapy Exclusion Criteria: * Unable to participate in behavior weight loss * Stroke, heart attack, end stage liver disease, or end stage kidney disease during the last 6 months. * Currently on a GLP-1 agonist * Currently on insulin
Where this trial is running
Kansas City, Kansas
- University of Kansas Medical Center — Kansas City, Kansas, United States (Recruiting)
Study contacts
- Study coordinator: Principal Investigator
- Email: mjavellana@kumc.edu
- Phone: 913-588-0885
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.