Web-based tools to enhance resilience and well-being
Official title: The WISER Study: Web Based Methods for Enhancing Resilience
Run by Duke University · NCT05636072 · Data updated 2026-11-12
This study is testing whether online tools that help boost resilience can improve well-being and reduce burnout in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 8000 (estimated) |
| Sponsor | Duke University Academic / other |
| Locations | 1 site (Durham, North Carolina) |
| Status | Recruiting |
| Started | November 1, 2022 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | April 8, 2026 |
| Trial ID | NCT05636072 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and over, particularly those working in healthcare settings.
✕Probably not a fit
Patients who are not proficient in English or lack basic computer skills may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This research focuses on evaluating the effectiveness of web-based resilience tools designed to improve well-being among adults, particularly targeting burnout. Participants will engage with various positive psychology activities, such as reflecting on positive experiences or writing letters of gratitude, all conducted online. The study will assess the impact of these tools on stress, depression, and burnout through a series of electronic surveys administered before, after, and at follow-up intervals. The study aims to gather data on the psychological effects of these interventions over time.
Why it matters
Potential benefit: If successful, this study could provide valuable online resources to help individuals improve their mental well-being and resilience against burnout.
How similar studies have gone: Other studies have shown promise in using web-based interventions for mental health improvement, suggesting a potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults 18 and over are considered eligible for the study. A sub-sample will include employees (including but not limited to frontline caregivers, support staff and management) of the Duke University Health System, as well as external health systems. All participants will be invited to participate in one or more of the online tools. The investigators will allow the participation of any clinical areas/healthcare worker groups whose leaders express interest in building resilience. The investigators are targeting healthcare workers for recruitment in the study, but adults 18+ are eligible to participate in any of these tools. Identification as a healthcare worker or not is part of data collection in every tool. Exclusion Criteria: * Adults who are not proficient in English, do not have basic computer skills, or who have prohibitive vision or hearing disabilities will be excluded from this study as they will be incapable of full participation in the intervention and/or the survey process.
Where it's running
-
Duke University Health System
Durham, North Carolina, United States Recruiting
Study contacts
- Principal investigator: John B Sexton, PhD — Duke
- Study coordinator: John B Sexton, PhD
- Email: bryan.sexton@duke.edu
- Phone: +1 919 681 4949
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.