Web-based support for colorectal cancer patients and their caregivers

A Web-Based Dyadic Intervention to Manage Psychoneurological Symptoms for Patients With Colorectal Cancer and Their Caregivers

Not applicable Interventional Emory University · NCT05663203

This study is testing a new online support program to help colorectal cancer patients and their caregivers manage symptoms like fatigue and depression during chemotherapy.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment56 (estimated)
Ages18 Years and up
SexAll
SponsorEmory University Academic / other
Drugs / interventionschemotherapy
Locations1 site (Atlanta, Georgia)
Trial IDNCT05663203 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates a web-based dyadic intervention designed to help manage psychoneurological symptoms in patients with colorectal cancer undergoing chemotherapy and their caregivers. The study involves developing a tailored intervention based on interviews with patient-caregiver dyads, followed by usability testing of the prototype. The feasibility and acceptability of the intervention will be assessed in a pilot trial with 20 dyads, measuring outcomes such as fatigue, depression, sleep disturbance, pain, cognitive dysfunction, and quality of life over an 8-week period.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older diagnosed with colorectal cancer, currently receiving chemotherapy, and experiencing at least two psychoneurological symptoms.

Not a fit: Patients with a Karnofsky Performance Scale score below 50 or caregivers with severe diseases may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life and symptom management for colorectal cancer patients and their caregivers.

How similar studies have performed: Other studies have shown promise in using web-based interventions for symptom management in cancer care, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
INCLUSION CRITERIA

Patients:

* Age \>= 18 years
* Diagnosed with colorectal cancer
* Life expectancy \> 12 months
* Receiving active chemotherapy
* Self-reported at least two psychoneurological symptoms (based on the symptom measures' cutoff scores)
* Identified primary caregiver (i.e., family members or significant others identified by the patients as their primary source of emotional and physical support)
* Access to the Internet
* Fluent in English

Caregivers:

* Age \>= 18 years
* Primary caregiver
* Access to the Internet
* Fluent in English

EXCLUSION CRITERIA

Patients:

• Karnofsky Performance Scale \< 50

Caregivers:

• Have severe diseases (e.g., cancer, heart disease)

Where this trial is running

Atlanta, Georgia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Colorectal Carcinoma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.