Wearable and AI-guided diet and exercise program for weight loss

Effectiveness of a Wearable Device and AI-Supported Diet and Exercise Intervention in Obese Adults-a Quasi-experimental Design Study

NA · National Taiwan University Hospital · NCT06630663

This study will test whether adding a wearable device and AI apps to a personalized 6-month diet and exercise program helps overweight and obese adults (BMI ≥24 with obesity-related conditions) lose weight.

Quick facts

PhaseNA
Study typeInterventional
Enrollment120 (estimated)
Ages20 Years and up
SexAll
SponsorNational Taiwan University Hospital (other)
Locations2 sites (Taipei, Taipei and 1 other locations)
Trial IDNCT06630663 on ClinicalTrials.gov

What this trial studies

Researchers at National Taiwan University Hospital recruited overweight and obese adults and collected baseline body composition and biochemical measures including circulating galectin‑1. Of 142 eligible participants, 98 entered a personalized 6‑month weight‑loss program and 44 served as controls; one group used a wearable device and AI apps alongside diet and exercise guidance while the other followed a standard program. Outcomes included weight loss, body composition changes, and biochemical markers related to adipose tissue and inflammation. Participants attended outpatient clinic visits for assessments throughout the 6‑month period.

Who should consider this trial

Good fit: Adults aged 20 or older with BMI ≥24 kg/m2 and at least one obesity-related comorbidity who can use a wearable device and smartphone app and attend clinic visits.

Not a fit: People with recent large weight changes, prior bariatric surgery, untreated psychiatric disorders, use of medications that affect body weight, or inability to use the device or return for clinic visits may not qualify or benefit.

Why it matters

Potential benefit: If successful, this approach could help overweight and obese adults lose more weight and improve body composition and related inflammatory markers such as galectin‑1.

How similar studies have performed: Other digital and wearable-based lifestyle interventions have produced modest but clinically meaningful weight loss in some trials, so the approach has supporting evidence but variable results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. At least 20 years of age
2. BMI ≥24 kg/m2 plus one or more obesity-related comorbidities such as hypertension, diabetes, hyperlipidemia, sleep apnea syndrome, or nonalcoholic fatty liver disease
3. Able to use a wearable device and an app
4. Able to sign the informed consent form after receiving a detailed explanation of the study

Exclusion Criteria:

1. Unable to finish the self-administered questionnaires
2. Unable to complete body composition assessment (bioimpedance analysis and abdominal echo), hand grip test, and blood sampling
3. Unable to return to our clinics at the scheduled time

Where this trial is running

Taipei, Taipei and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Obesity and Obesity-related Medical Conditions, obesity, weight loss, galactin-1, diet and exercise program

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.