Voice features linked to pulmonary hypertension and heart disease
Cardiovascular Disease/ Pulmonary Hypertension and Voice Characteristics Study
Mayo Clinic · NCT07311044
This project will see if short voice recordings can show whether adults getting routine echocardiograms at Mayo Clinic have pulmonary hypertension and how severe it is.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 7000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic (other) |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT07311044 on ClinicalTrials.gov |
What this trial studies
This is an observational study enrolling adults referred for clinically indicated diagnostic echocardiograms at Mayo Clinic Rochester. Investigators will collect brief voice recordings and compare signal characteristics with echocardiography findings and clinical data to look for patterns associated with presence and severity of pulmonary hypertension and other cardiovascular disease. Patients with known voice disorders are excluded to avoid confounding voice-pathology effects. The goal is to identify noninvasive voice-based markers that correlate with established imaging measures.
Who should consider this trial
Good fit: Adults (18 and older) scheduled for or undergoing a clinically indicated diagnostic echocardiogram at Mayo Clinic Rochester who do not have a known voice disorder.
Not a fit: People under 18 and those with a known primary or secondary voice disorder are not eligible and are unlikely to benefit from the voice-based approach.
Why it matters
Potential benefit: If successful, this could provide a simple, noninvasive way to screen or monitor pulmonary hypertension using brief voice recordings, enabling earlier detection or easier follow-up.
How similar studies have performed: Some prior work has linked voice features to cardiovascular risk and disease, but using voice analysis specifically to detect pulmonary hypertension is relatively novel and not yet well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All individuals who present for a routine elective, clinically indicated, diagnostic echocardiogram at the echocardiography laboratory at Mayo Clinic * All individuals who have had a clinically indicated, diagnostic echocardiogram at the echocardiography lab at Mayo Clinic before a scheduled procedure in the cardiac catheterization lab at Mayo Clinic * All individuals who have had a clinically indicated diagnostic echocardiogram at the echocardiography lab at Mayo Clinic and have an appointment in any CV outpatient clinic. Exclusion Criteria: * Known history of voice disorder either primary or secondary to neuromuscular or other pathology * Patients under the age of 18 years
Where this trial is running
Rochester, Minnesota
- Mayo Clinic — Rochester, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: Amir Lerman, M.D. — Mayo Clinic
- Study coordinator: Diana Albers
- Email: albers.diana2@mayo.edu
- Phone: 507-255-6884
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Pulmonary Hypertension, Cardiovascular Diseases