Clinical trial Recruiting at 2 sites Phase 2 Interventional Ages 10 to 18

Vitamin D's role in treating adolescent scoliosis

Official title: The Role of VitD in Rehabilitation of Idiopathic Adolescent Scoliosis

Run by University of Ioannina · NCT03582917 · Data updated 2026-11-12

This study is testing if giving vitamin D to teenagers with scoliosis can help improve their spinal shape and health over two years.

More Scoliosis trials

Quick facts

PhasePhase 2
Study typeInterventional
Ages10 Years to 18 Years
SexAll
Enrollment80 (estimated)
SponsorUniversity of Ioannina
Academic / other
Locations2 sites (Asvestochóri and 1 other locations)
StatusRecruiting
StartedSeptember 20, 2018
Main results expectedDecember 20, 2025
Study endsDecember 20, 2025
Registry record updatedDecember 6, 2024
Trial IDNCT03582917 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adolescents diagnosed with idiopathic scoliosis and a Risser sign of less than 3-4.

Probably not a fit

Patients with neuromuscular diseases, metabolic disorders, or significant organ dysfunction may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective study aims to investigate the impact of vitamin D on the development and correction of spinal deformities in adolescents with idiopathic scoliosis. Participants will undergo a thorough medical history assessment, including measurements of age, body size, and bone density. They will be divided into two groups based on their vitamin D levels, with those having low levels receiving supplementation. Follow-up evaluations will occur every six months for two years, incorporating clinical, laboratory, and radiological assessments to monitor progress.

Why it matters

Potential benefit: If successful, this study could enhance treatment options for adolescents with scoliosis by utilizing vitamin D supplementation to improve spinal health.

How similar studies have gone: While the role of vitamin D in bone health is well-established, this specific approach in treating adolescent scoliosis is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Idiopathic Adolescent Scoliosis
* Risser sign \<3-4

Exclusion Criteria:

* Neuromuscular diseases
* metabolic disease
* Liver, lung, thyroid and parathyroid gland disorders.

Where it's running

  • Papanikolaou General Hospital
    Asvestochóri, Greece
    Recruiting
  • Department of Physical Medicine and Rehabilitation, University Hospital of Ioannina
    Ioannina, Greece
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.