Clinical trial Recruiting at 1 site Observational

Vitamin D Deficiency and BPPV: Is Low Vitamin D Linked to Vertigo Recurrence?

Official title: Association Between Benign Paroxysmal Positional Vertigo and Vitamin D Deficiency ; Sohag University Hospital Experience.

Run by Sohag University · NCT07491965 · Data updated 2026-11-12

This observational study tests whether adults with BPPV have different vitamin D levels compared with adults without dizziness at a hospital in Sohag, Egypt.

Quick facts

Study typeObservational
SexAll
Enrollment160 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag)
StatusRecruiting
StartedApril 1, 2026
Main results expectedSeptember 1, 2026
Study endsOctober 1, 2026
Registry record updatedJune 18, 2026
Trial IDNCT07491965 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults diagnosed with idiopathic BPPV based on a positive Dix-Hallpike maneuver, compared with adults without vertigo or BPPV attending ENT clinics.

Probably not a fit

Individuals with secondary vertigo or conditions affecting vitamin D metabolism may not experience benefit from the study findings for BPPV risk guidance.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Benign paroxysmal positional vertigo (BPPV) is a common cause of vertigo related to head position. This study investigates whether vitamin D deficiency is associated with BPPV by comparing adults with idiopathic BPPV to adults without vertigo attending ENT clinics. It uses the Dix-Hallpike maneuver for diagnosis in cases and controls, and examines vitamin D status as a potential metabolic factor. By focusing on a tertiary-care center in Upper Egypt, the study aims to clarify whether vitamin D metabolism may influence otoconia maintenance and BPPV risk. The findings could inform future preventive or therapeutic strategies if a link is identified.

Why it matters

Potential benefit: If a link is found, it could lead to new prevention or management approaches for BPPV, such as vitamin D screening or supplementation in at-risk individuals.

How similar studies have gone: Previous research has suggested associations between vitamin D deficiency and BPPV, but the strength and consistency of evidence vary across populations.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Cases: Adults with a confirmed diagnosis of idiopathic BPPV based on positive Dix-Hallpike maneuver (nystagmus and vertigo lasting \<1 minute).

  * Controls: Adults attending ENT clinic without history of vertigo or BPPV, confirmed by negative Dix-Hallpike test.

Exclusion Criteria:

* Known causes of secondary vertigo (e.g., Meniere's disease, vestibular neuritis, central vertigo).

  * Conditions affecting vitamin D metabolism (e.g., chronic kidney disease, malabsorption syndromes, hyperparathyroidism).
  * Use of medications interfering with vitamin D levels (e.g., anticonvulsants, glucocorticoids) in the past 3 months.
  * Pregnancy or lactation.
  * Inability to provide consent.

Where it's running

  • Sohag University Hospital
    Sohag, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Epley vs. Semont-plus maneuver for posterior canal BPPV

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    Recruiting Military Hospital 175 · Ho Chi Minh City · NCT07787559

  • Epley maneuver for treating dizziness in the emergency department

    This trial tests whether doing the Epley maneuver, versus a sham maneuver, helps adults with posterior canal BPPV who come to the emergency department feel less dizzy.

    Recruiting American University of Beirut Medical Center · Beirut · NCT07111000

  • Investigating BPPV in Elderly Patients in Primary Care

    This study is testing if simple balance tests for dizziness in older adults can help find hidden cases of BPPV and improve their quality of life while reducing their fall risk.

    Recruiting Region Stockholm · Saltsjö-Boo, Stockholm County · NCT06643702

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.